Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15980 Roscovitine GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 38 GATA3; NRBF2; EGR4; RNF111; ZSCAN31; HOXA1; ELF4; LPIN2; NR4A1; PFDN5; VGLL4; ZNF410; ZNF12; EGR2; NFE2; ERG; PITX2; TFEC; NR4A2; ZNF146; TRIP6; TAL1; SMARCD3; MYB; ZNF165; NKX2-2; ELF5; CITED2; MNDA; KLF2; FOS; EGR3; TBX3; ZFPM2; JUP; BHLHE41; TRIM29; PBX3
Down-regulation 39 IKBKAP; CARM1; HOXA11; ZMYND8; ETV4; ETS1; TLE1; PAX8; HMBOX1; CERS6; ALX1; MXD4; MLXIP; IRF8; PITX1; POU4F1; KLF6; PBXIP1; CNOT3; CUX1; POU2AF1; TXNIP; SIAH2; LOXL2; BCL11A; EMX2; MSX1; HEY1; PIR; OSR2; KLF9; CITED1; SOX9; ZBTB38; NR2F2; ETV1; CREB1; ZNF91; HOXC6