Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15979 Roscovitine GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 21 MEF2C; GATA3; RORA; KLF6; FOSB; FLI1; RBBP8; ZNF131; KLF2; ERG; KLF11; IFI16; ELF5; TCF4; DACH1; FOS; ESR1; ID3; EGR3; HOXC6; CREB1
Down-regulation 21 FOXF1; ATF5; LITAF; AES; RREB1; EHF; HMGA1; TXNIP; USP22; INSM1; FOXA2; FOXF2; MEIS1; PITX1; CALR; VPS72; ZIC1; SOX9; NR2F1; SATB1; BASP1