Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15977 Torin-2 GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 301 PNRC1; CARF; ZNF688; MED12; TSC22D3; ZKSCAN4; ZNF224; ELF4; NR5A1; CEBPD; ZNF611; CDIP1; SUPT3H; ZNF573; ZNF358; HBP1; PHF1; REL; BTG1; ZNF506; FOXD3; LZTR1; EPAS1; ZNF667; ZNF362; MAML3; TULP1; ZNF160; FEZF2; RFX1; SCAI; POU2F3; ZIC3; CALCOCO1; SPI1; ZNF500; CREBL2; TBX5; ZNF440; ZNF80; ZNF665; TULP2; HMBOX1; ZNF701; ZXDB; POU6F2; CRX; ZNF721; DCC; GSC2; ZNF426; ZBTB3; ZNF345; PFDN5; ZNF93; ZSCAN9; HOXD1; PRDM9; NEUROD1; TGFB1I1; YEATS2; ZNF264; SOX4; MLLT1; TBX6; ZNF44; INSM1; ZNF133; ZNF780B; ZNF529; HNF4G; HOXD3; ZNF768; TFEC; ZNF136; POU1F1; TFAP2A; PPARA; ZNF674; ZNF91; SCRT1; DYRK1B; ZNF81; ZNF254; NEUROG2; ZNF589; SOX3; GCM2; ZNF219; BRDT; LYL1; ZNF407; FOXH1; ZNF257; SOX12; ZNF430; SRY; RING1; ZBTB16; TLX2; PHF20; NHLH1; SHOX; ATOH1; OVOL2; ST18; DAXX; CBX7; ATF3; ZKSCAN1; ZNF652; ZNF74; FOXI1; MED16; NEUROG1; GATA6; THRB; PRDM2; FOXF2; JUP; TBR1; ZNF225; EZH1; BNC1; ZNF654; AFF2; TP73; ZFP69B; PHIP; DLX4; SOX5; TOX3; TAF7L; RORA; MNT; ZSCAN18; TCF7; PAWR; ZNF334; ZBTB20; PBXIP1; ZNF135; EP300; GCM1; ING4; ZNF682; MAFF; TAF1; VGLL1; ZNF117; HSF1; L3MBTL1; SUPT5H; HIRA; BAZ2B; MXI1; PRDM12; GBX2; ZNF423; NR1H3; ZBTB44; SOX21; TCF7L2; ID4; PEX14; ZKSCAN8; FOXF1; ZNF536; EVX1; BRWD1; GFI1B; PRDM14; SALL2; FOSL2; IRF6; DLX2; ZNF154; CIR1; MEF2C; SMAD6; HAND1; SRCAP; ZNF141; HMGA2; PRRX2; TDP2; TBX1; IRF9; ZNF623; CSDC2; CHD2; MYBL1; HDAC5; ZNF165; LHX3; RFXANK; NAB2; NKX2-1; NFKB2; CBX2; ZMYND8; RBPJ; PLAGL1; CTBP2; ZNF112; BNC2; SIM1; PCGF3; SOX18; BARX1; CCNT1; NR1I2; ZNF223; LIN28A; KLF3; MED14; CAMTA2; E2F5; EHF; ZBED2; SOX2; RORC; MZF1; BCL6; ZFPM2; TSC22D1; HOXB1; CEBPE; SMARCC2; KLF11; HIVEP1; ZNF711; ZNF175; AEBP1; LMCD1; MEIS2; ZHX2; PPP1R13L; HIC2; SOX17; LOXL2; NFATC1; BHLHE41; ERBB2; ERBB4; TGIF1; STAT4; TRIM29; TGIF2; PDLIM1; DLX5; STAT6; RARG; SMARCA1; NR5A2; SPIB; BTAF1; ZNF331; NCOA2; BBX; BCL11A; CBFA2T3; ZFP36L2; SNAI2; ZNF512B; MAF; VPS72; WNT4; HHEX; FOXN3; TRIB3; ARNT2; TULP3; KLF5; ZNF232; PAX6; TCEA1; AHR; TCEA2; BACH1; NR0B1; FOXA2; TOX; TAL1; YAP1; CREM; KDM5B; NFE2L3; TCF4; AR; NFATC4; MEIS1; LITAF; WT1; TWIST1; SOX9; TBX3; TFAP2C; TRPS1; SPDEF; ARID5B
Down-regulation 93 CCNA2; TCERG1; EZH2; MYBL2; SUB1; MYCBP; PARP1; GTF2A2; FOXM1; EED; HMGB1; CENPF; WHSC1; HSF2; RUVBL1; ZBTB24; BATF3; ATF5; SUV39H1; WDHD1; ITGB3BP; BRCA1; PSIP1; ADRB2; BAZ1B; YEATS4; PTTG1; CCDC59; BMI1; BCLAF1; UBP1; HOXB7; PSMC3IP; RBM14; ING3; PA2G4; CBFB; NUP62; BLM; ZNF468; CTR9; MED1; SETD2; NPAT; HOXA10; RBBP8; HLTF; SIM2; RUVBL2; HNRNPD; DNMT3B; MED6; TFDP1; RAN; HDAC1; STAT1; RBBP4; HMGB2; RHOA; C1QBP; SFPQ; RNF6; CCNE1; E2F8; PURA; HMGB3; TRIM28; NEDD8; CCNC; STAT3; CEBPA; CRY1; CEBPZ; CBX3; BAZ1A; NR2F2; AFF1; PIAS3; SAP30; MYB; ENO1; YWHAB; FOSL1; BIRC2; MSX1; JARID2; LEF1; SMAD1; ETV1; ELK3; HOXC6; EMX2; EGR3