Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15975 Torin-2 GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 228 TSC22D3; CALCOCO1; HBP1; ZNF611; ZNF358; SOX4; ZNF160; CDIP1; EP300; ZNF224; EZH1; CERS4; HDAC5; PNRC1; ZNF500; PBXIP1; ZNF669; ZSCAN9; IRF9; ESR2; ZNF688; GLI2; RING1; ARID5A; CRX; NR5A1; ZNF117; HINFP; ZNF219; SPI1; ZNF768; NFATC3; PCGF3; ZBTB16; SRCAP; SIX6; MAFG; ZNF76; FEZF2; ZNF701; NHLH1; ZNF573; ELF4; ZNF33B; MED15; ZNF430; MKL1; AFF2; ZNF264; PROP1; ZNF506; KLF7; THRB; ZNF44; EVX1; MED12; MNT; TEAD3; ZNF589; ZNF34; ZBTB43; ZNF415; TCEA2; CRTC1; TGFB1I1; JUND; ZNF665; RSF1; HSF4; HMBOX1; MED25; KDM4C; MTA1; POU2F2; ZMYND8; MEF2C; ZNF345; L3MBTL1; GBX1; MEF2D; LZTR1; REL; ING4; BTG1; TCF7L2; ERBB2; ZNF91; ARID3B; TBX21; ATF4; SKI; ID4; ZFHX3; RORC; ZBTB7A; PRDM2; WIZ; HOXA3; ZNF646; ZNF426; KLF13; NAB2; ZNF74; CIR1; ATOH1; NFIX; MAFF; JUP; ZNF652; NKX2-1; SALL2; SETDB1; VPS72; ZNF93; CEBPE; ZBTB17; ZBTB44; PPP1R13L; ZKSCAN1; STAT2; DLX5; ZNF667; BRD4; PHF1; CUX2; NR2C1; NR1H2; TSG101; MXI1; ZNF350; BARX1; CBX7; ZNF671; IRF6; AES; ZIC3; HMX1; RARG; RFXANK; ZNF562; IKZF1; PAWR; PDLIM1; HOXB1; TCEB2; ZNF268; ZNF205; FOXO3; TCF3; KAT2B; GFI1B; TSC22D4; TCF7; BPTF; TXNIP; HDAC9; BACH2; ZNF394; ZBTB20; OVOL2; ARL2BP; SP140L; IRF7; HDAC7; TRIM22; SSBP3; GATA1; ZNF43; BCL3; HEY2; ZNF711; FOXI1; DLX2; SPDEF; ZNF721; SMARCD3; FOSL2; ZNF580; JAK2; SOX17; HIRA; PHF20; RORA; HOXD1; NFE2; SHOX2; WNT4; ERBB4; NFAT5; HIC2; AR; KLF11; NCOA2; CBFA2T3; BCL11A; INSR; SP100; STAT4; ATF3; ZNF165; MAF; TWIST1; TAL1; TRIB3; FOXO1; TGFB1; GATA6; ZNF423; ST18; TRIM29; ZFPM2; TCF4; ESR1; ZIC1; RELB; EMX2; TLE4; FOS; ZBED2; ZHX2; EHF; ZSCAN18; HOXB2; SSBP2; ARID5B; NFATC4; SNAI2; BHLHE41
Down-regulation 100 CCNA2; MYCBP; MYBL2; PARP1; TCERG1; USP22; RUVBL1; EZH2; GTF2A2; FOXM1; EED; TBP; C1QBP; NUP62; SUB1; HSF2; MNAT1; RBM14; TFDP1; PSMC3IP; CBFB; ADRB2; ITGB3BP; CCDC59; WDHD1; BRCA1; BCLAF1; MTDH; HLTF; TAF9B; TFAM; CHAF1B; CEBPZ; CENPF; PREB; HOXB7; SUV39H1; HMGB2; RNF6; ZNF200; NPAT; RUVBL2; HMGB1; PURA; AATF; RAN; TP53; SFPQ; HOXA10; TRIM28; UBP1; ORC2; SMARCE1; PA2G4; RNF138; RBBP4; HNRNPD; DNAJC2; DNMT3B; MED21; PTTG1; CRY1; CCNC; CTR9; CREBZF; BMI1; TSC22D2; NR2F2; TBPL1; MED1; POU4F1; BLM; XBP1; PMS1; PSIP1; BAZ1A; CBX3; KLF10; ZBTB18; RFX5; STAT3; WWTR1; CHD1; FOSL1; LEF1; ETS2; MTF2; ELK3; TOB1; ID2; HOXC6; MYB; ELF1; SAP30; IRF4; IKBKAP; ETV1; AFF1; ID1; CREB1