Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15974 Torin-2 GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 176 TSC22D3; PNRC1; NCOA3; HBP1; ZBTB16; ZNF688; HDAC5; SOX4; CALCOCO1; ZNF500; MAFG; PHF20; ZNF358; FHL2; ZNF611; ZNF532; ZNF160; TBX6; CEBPD; MNT; CREBL2; IRX4; ZNF440; TULP1; EZH1; ATF4; NR5A1; ZNF362; DYRK1B; CRX; CBX7; TGFB1I1; SCAI; ZNF408; NPAS1; WNT4; SRCAP; EN1; DLX4; MYF5; YEATS2; CARF; CIR1; LZTR1; HINFP; TLX2; ZNF33B; HIF3A; PRDM2; SRY; ELF4; PHF1; ZNF44; FOXO3; APBB1; ZNF573; ZNF768; HOXD1; ZNF224; ZNF667; ZNF345; SPI1; GBX2; SMAD6; NFKB2; HIVEP2; PBXIP1; L3MBTL1; ERBB2; IRF6; CERS4; ZMYND8; ZKSCAN1; SP100; HSF1; INSR; IRF9; CNOT2; ZNF536; EP300; ZNF93; ING4; LMCD1; STAT2; SUPT3H; PSPC1; EVX1; RBPJ; DDIT3; TCEA2; TRIM22; PRDM12; ZNF623; HMBOX1; HDAC9; FEZF2; NFE2L1; ZNF112; TSG101; ZNF217; BCL10; INSM1; ZNF721; VGLL1; FOXF2; TFDP2; PAWR; PITX2; ZNF268; JUP; NKX2-1; SOX18; HTATIP2; KLF7; ZNF117; ZNF665; KLF13; NAB2; ZFP36L2; OVOL2; FOSL2; BPTF; JUND; ELF3; BAZ2B; SMARCC2; ZNF415; TFEC; BTG1; ZBTB20; NFE2; ERBB4; PHIP; BCL11A; GRHL2; DLX5; UBE2B; MXI1; GATA6; SP110; VDR; TRIB3; OSR2; ZSCAN18; TBL1XR1; VPS72; SNAI2; AEBP1; SOX17; HIC2; ZNF165; CARHSP1; MYRF; SOX2; TCF7L1; NCOA2; ARID4B; ZNF83; TAL1; KLF5; AHR; FOXO1; MEOX2; ST18; TCF7L2; NPAS2; ZNF91; ZNF423; ID4; TRIM29; TCF4; ARNT2; TBX3; FOXO4; ARID5B; BHLHE41
Down-regulation 89 CCNA2; MYCBP; PARP1; GTF2A2; TCERG1; MYBL2; RUVBL1; TFAM; EED; EZH2; HDAC2; SUB1; HMG20B; SMARCA4; NUP62; PTTG1; RBM14; SUV39H1; HLTF; HMGB1; YEATS4; CBFB; ING3; BCLAF1; ZNF672; ITGB3BP; PIAS2; BAZ1B; TOPORS; SMARCA5; RNF138; RAN; TAF9B; WDHD1; PSIP1; SMAD5; CHD7; C1QBP; BMI1; ZBTB38; TRRAP; RBBP7; CCDC59; HNRNPD; XRCC6; SSRP1; UBP1; TFDP1; GATAD2A; CENPF; FOSL1; PBRM1; HES1; PMS1; TP53; RNF4; BAZ1A; CRY1; CCNE1; SMAD1; HMGB2; PA2G4; MED1; RBBP4; PITX1; ING2; CHD1; NR2F1; RUVBL2; STAT3; ENO1; BLM; BBX; BRCA1; LEF1; SATB2; HOXB7; IRX5; TRIM28; JARID2; RYBP; CDK2; TOB1; ETV1; NR2F2; BASP1; EGR3; CREB1; SATB1