Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15973 Torin-2 GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 353 TSC22D3; NR3C1; PNRC1; ZBTB16; NCOA3; CALCOCO1; HBP1; HDAC5; SOX12; EP300; ZNF667; ZKSCAN4; ELF4; ZNF688; ZNF669; ZKSCAN1; NR1I2; SPI1; ZNF701; YEATS2; ZNF611; MED12; RFX1; HINFP; CBFA2T2; ZNF573; IRX4; CIR1; NR5A1; LZTR1; ZNF219; ZNF430; ZNF345; SCAI; ZSCAN9; ZNF222; NEUROG3; HDAC9; ZNF362; ZNF358; SIRT2; EZH1; FOXO3; TULP1; TBX5; FEZF2; IRF9; FOXD3; FOXH1; ZNF44; SCRT1; JUP; ZNF532; ZNF408; TGFB1I1; ZNF426; DMTF1; ZBTB44; ZNF467; MYF5; APBB1; GLI2; SOX3; ZNF506; ZBTB3; ZNF224; CBX4; ZNF225; BTF3; CRX; ZNF589; SRY; ZNF79; BTG1; ETV2; RING1; ERBB4; ZNF500; DYRK1B; POU6F2; PRDM9; ZNF34; HOXD3; ZSCAN16; EMX1; ZNF350; TGIF1; L3MBTL1; TBX1; TBX6; ZNF33B; TSG101; ZFHX3; ZSCAN2; HOXD1; ZNF682; HDAC6; FOXF2; SUPT3H; RSF1; GBX2; HLX; LMCD1; ZNF529; TP73; GSC2; SALL2; CDIP1; ZNF112; SIX6; PRDM14; BRD4; ZNF354A; HOXC13; HIF3A; CREBL2; ZNF93; ZNF665; NFKB2; HOXC4; HMX1; LIN28A; ZNF177; KLF11; PKNOX2; ZNF81; CARF; AEBP1; PHF1; ZNF214; ZNF768; NR1I3; ZNF223; GLI1; LDB1; TFAP2A; ZNF235; MED14; ZNF257; ZNF394; BPTF; ZNF606; IRF7; ZNF778; PRDM12; PHF20; ZXDC; TCF7L1; ZNF239; PBXIP1; FOXK2; STAT2; ZNF334; ZNF135; PRDM4; AFF2; GFI1; JUND; SOX18; ZNF331; ARID5A; CDX1; NAB2; HOXA3; SSBP3; PLAG1; ZFP69B; TEAD3; ZNF155; MEF2D; PRDM2; BACH1; CIITA; ZNF91; SKIL; SIX3; MYRF; HIVEP1; WNT4; ARID3A; EVX1; ZNF160; MNT; SETDB1; SUPT6H; CHD2; LYL1; ZNF671; PHIP; LHX3; SRCAP; ZBTB20; ING4; TAF6L; CERS4; ZNF217; GTF2IRD1; KDM5C; ZNF154; DLX2; BNC2; TCF21; GFI1B; THRB; ZBED1; ZNF623; HTATIP2; FOXN3; TCF25; EHMT2; ATF4; ZNF12; PBX1; SMARCC2; NFE2L1; MXD4; TCF15; NR1H2; TRIM24; ZNF75D; HOXB13; UBE2B; ZNF175; KLF13; ELF3; DAXX; ZBTB43; KDM5B; CBX7; ZNF195; ZNF85; TCF7L2; ZNF304; BRWD1; ERBB2; NKX2-1; SOX2; PBX2; VPS72; DDIT3; TLX3; SPIB; ZNF264; ZIC3; MZF1; ZNF205; STAT3; ZFY; TRIB3; ZMYND8; ZNF580; ZNF423; ZNF415; TCEA2; PPP1R13L; TGIF2; BCL11A; TBX21; HOXB1; OSR2; MEOX2; GATA6; SP100; NFE2L3; ZNF329; PTRF; FLI1; ZSCAN18; CUX2; KAT2B; ZNF117; IRF6; FOXO1; OVOL2; ST18; NPAS2; TOB1; FOXG1; MAF; RORA; NCOA2; BCL3; MED13; TDP2; PITX2; NFATC1; PAWR; SOX10; ZNF43; ZKSCAN7; KLF10; MYCL; INSM1; TULP4; NR1H3; ZNF512B; ZNF544; ZNF165; BRD2; RARG; PLAGL1; HIC2; REL; ARNT2; TSC22D1; KLF6; SMARCA1; NR1D2; TCF3; INSR; TRPS1; MXI1; ZNF83; TULP3; SOX13; CREB3L2; MAZ; AR; AHR; ARID4B; CTBP2; SOX17; TP63; TRIM22; TFEC; JUN; HOXB2; GRHL2; ESR1; THAP11; NR0B1; ID1; PBX3; IRF8; ZFPM2; TAL1; MEIS2; ZBED2; MAFB; TOX; KDM5D; SNAI2; ARID5B; DACH1; HOXB6; TGFB1; FOXO4; SSBP2; TRIM29; ZHX2; NFATC4; CREB1; NFATC3
Down-regulation 106 PARP1; CCNA2; MYCBP; GTF2A2; EZH2; EED; ADRB2; HDAC2; NUP62; PURA; RUVBL1; HOXA5; RBM14; ATF6; SMARCA5; SUB1; TFAM; RAN; ZNF672; ETS1; GABPB1; TBP; NFKB1; MED21; SFMBT1; HLTF; RNF14; BMI1; UBE2I; BATF3; TLE1; CBFB; WHSC1; GABPA; TAF9; TFDP1; ITGB3BP; BCLAF1; HOXA10; UBE2L3; RUVBL2; TBPL1; ENO1; DRAP1; RNF138; SUV39H1; RBBP4; CEBPZ; PAX8; FOSL1; SMAD5; C1QBP; ZBTB18; HOXA1; MED1; PIAS2; ECD; CCDC59; RHOA; TRIM32; MTDH; RBBP7; PREB; LEF1; STAT1; HNRNPD; CCNC; IRX5; PA2G4; HMGB1; DNAJC1; PTTG1; SMAD1; BRCA1; BCL11B; EGR1; XBP1; SMARCE1; SPEN; ILF2; GTF2I; CHD7; MED24; TRIM28; ATF1; SSRP1; TSC22D2; KLF2; DNMT3B; HMGB2; ELK3; CCNE1; NR2F2; MAGED1; EMX2; SMAD7; MSX1; ID2; VGLL4; PUF60; EGR3; ZBTB38; MECOM; NR2F1; ETV1; EGR2