Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15971 Pelitinib GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 226 PPARG; TSC22D3; CALCOCO1; NFKBIA; TEAD3; ZNF500; ZNF611; TRIM22; ZNF536; ZNF688; ZBTB16; ARHGAP35; ATF3; AFF2; HMBOX1; TOX3; BTG1; GLI2; IRF6; PBXIP1; ZNF44; CEBPD; HDAC5; MYF5; REPIN1; KDM4A; MXI1; PNRC1; RING1; ZNF629; OSR2; ZNF33B; ZNF160; NR1H3; FOXO3; HIF3A; FOXJ1; MED12; ZNF358; L3MBTL1; PBX1; BCL6; ZNF34; TLE2; ZNF345; ZNF337; ZFHX3; IRF9; GCM1; EBF2; TRIM29; NFKB2; NR5A1; PDLIM1; HMGXB3; ZNF3; SIRT2; PRDM2; ASCL3; ZNF467; SALL2; EPAS1; ZNF112; ZNF768; ERBB2; ZNF224; ZSCAN31; ZBTB44; PEG3; RSF1; CREBL2; ZMIZ1; FOXJ3; MKL1; LZTR1; ZNF257; STAT2; CERS4; LDB1; TCF7L2; SREBF1; THRB; NR0B2; TRIM16; BNC2; ZNF665; MZF1; CREB3L2; STAT5A; ZNF136; KLF4; BRD4; TFEC; ZSCAN9; FOSB; MEIS1; ID2; WNT4; TRIM24; TBX1; FOSL2; ZNF646; ZNF529; ZNF91; ZNF74; SRCAP; KAT2B; MYCN; TFCP2L1; SETDB1; BAZ2A; ZNF667; ING4; GLI1; SIM1; BPTF; SIN3B; ZKSCAN1; NFAT5; CSDC2; ZNF264; INSM1; ELF3; AR; HSF1; NHLH2; ZNF350; SIX3; REL; IRF7; ZNF573; ZNF711; ZNF721; TCF7L1; CHD8; JUP; TP53; SMARCD3; ATN1; NR1H2; ZNF93; ELF4; NEUROD1; ZNF512B; ZNF430; SSBP2; TP63; MEN1; ZBTB48; KLF5; LITAF; RARG; MECOM; ZNF165; HIVEP1; SOX4; ZNF587; MITF; INSR; ATF4; ZBTB17; SMARCA1; SMARCD2; TCF7; CBX7; FOXI1; MEOX2; TLE1; HBP1; MYRF; ST18; AES; ZNF415; SIX2; IRF1; BASP1; ZNF544; SNAI2; AHR; SP100; ZBTB43; SMAD6; ID3; GRHL2; CREG1; MXD4; ZNF652; ARID1A; YAP1; PLAGL1; ZIC1; ZSCAN18; TULP3; RXRA; CD3D; HIRA; SOX13; NCOA2; DACH1; ZBTB20; MED13; HEY1; GATA2; FOXA1; TBX3; ID4; ZNF117; ZNF331; ID1; MYCL; MNDA; BACH2; TRIB3; VPS72; ASCL1; TCF4; TXNIP; FOXO4; ZNF423; ARNT2; GATA6; PCGF2; ARID5B; HOXB6; MAF; NFATC4
Down-regulation 100 CCNA2; MYBL2; HMGA2; SUV39H1; FOXM1; HMGB2; FOSL1; HMGB1; PARP1; GTF2A2; PTTG1; HDAC2; CENPF; CHAF1B; BAZ1B; HSF2; TAF9B; DRAP1; WHSC1; DR1; RUVBL1; WDHD1; PSMC3IP; HES1; SMARCA5; RNF14; SUB1; EED; MLX; MYCBP; BCLAF1; PA2G4; RAN; BRCA1; CCDC59; KMT5A; RBM14; YEATS4; ETV4; HNRNPD; EGR1; BATF3; RBL1; C1D; SMARCE1; ING2; EGR4; RNF4; NPAT; RFC1; ECD; TFAM; CRY1; HLTF; ASH2L; SFPQ; EGR3; DNAJC2; ARNTL; ITGB3BP; RBBP4; CCNE1; PSMC3; FOXD1; HMGA1; CBFB; CEBPZ; WWTR1; XBP1; NUP62; ETV5; HOXC10; SATB2; CBX3; FOXG1; RBBP7; BLM; BMI1; IFI16; ILF2; YWHAB; TRIM28; SMAD1; TFDP1; HOXB7; TSC22D2; RBPMS; ELK3; BRIP1; KLF10; NR2F1; ZEB1; ETV1; CDK2; HOXC6; ZBTB38; ESR1; EGR2; SATB1; CREB1