Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15970 Pelitinib GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 280 TSC22D3; PNRC1; CALCOCO1; ZNF688; ZKSCAN4; BTG1; TRIM22; WNT4; NCOA3; HIF3A; PBXIP1; IRF6; TEAD3; ELF3; TRIM29; ZBTB16; HBP1; ZNF257; ZNF467; FOXO3; MYF5; PRDM2; SCAI; PBX1; SOX12; CARF; ZSCAN31; ZBTB3; IRX4; CERS4; VGLL1; AIP; SUPT7L; ZNF623; NFE2L2; ZNF16; HDAC5; ZNF337; ZNF669; CBX7; RING1; ZSCAN16; YEATS2; ZBTB40; ZNF768; ING4; ATF3; CEBPD; MAML3; TRIM16; ZNF512B; OSR2; ZNF362; WWC1; SOX3; ZNF358; NR5A1; KAT8; ZNF492; FOSL2; REL; ZNF33B; ZNF426; HMBOX1; ZNF34; CDIP1; SMAD4; ZNF354A; MEF2C; ZKSCAN1; TRIM24; ZNF345; ZNF12; ZNF124; ZNF423; TGIF1; ESRRA; CIR1; BCL6; ZNF629; ZBTB39; ZNF254; NR1I3; TP63; SMAD6; ZSCAN32; JUP; RSF1; ZNF529; ELF4; MYCL; INSR; KDM5A; NFE2L1; GRHL2; GATA3; ZSCAN9; ZNF264; ZNF224; SALL2; SETDB1; CDK9; CUX1; CSDC2; ZNF266; ZNF24; DYRK1B; ZFHX3; ZMIZ1; SIRT2; ZNF611; NHLH2; TAF11; STAT2; ZNF225; E2F5; ZNF112; MEIS1; FOXN3; THRA; FOXA1; ZNF652; ZNF219; ZBTB44; SIX5; ZNF3; NR0B2; NR3C1; IRF9; ZNF44; ZNF117; CHD3; SP2; EPAS1; SKI; MEIS2; TAF6L; TBX1; SRCAP; ZNF135; PRDM12; EZH1; ZNF184; ZNF91; DLX4; TERF2; ZNF350; ZNF268; ZNF136; L3MBTL1; NR2C1; ZNF510; BAZ2B; PAWR; NCOA1; SOX18; SOX4; ZNF226; GLI3; ZHX2; MEN1; TCF4; TCF7L1; ADNP2; ZNF155; TRPS1; PHF20; SOX2; HSF1; AHR; REPIN1; LMCD1; ZNF141; CREBL2; ZNF75D; MYCN; ZFPM2; GATA6; RARB; HIVEP1; ZNF331; KLF3; TFEC; FLI1; HEY2; LITAF; ID2; CBFA2T3; BCL11A; RARG; PPP1R13L; MXI1; PHF1; ARID1A; BNC2; TFAP2C; ERG; SKIL; TRAK1; TCF7L2; ZNF430; ID3; JAK2; ZNF665; ZNF711; ZNF304; MYRF; NFATC1; YAP1; IRF1; DAXX; ERBB2; FOXC1; ZNF415; SIX3; CREBZF; ZNF43; ZFP36L2; MXD4; TCEA2; ZMYM2; ZNF165; NAB1; MAFB; TULP3; RFX5; ERBB4; FOSB; ESRRG; HOXB13; FOXO1; HIC2; KAT2B; RORA; TFDP2; GLI2; DLX5; TAL1; SOX17; SSBP3; JUND; PDLIM1; NCOA2; STAT4; ID4; ELF5; CREB3L2; BACH2; ARID5B; ZNF551; SMARCD3; SOX13; ASCL1; HTATIP2; THAP10; SIAH2; HEY1; TBX3; CREG1; HIPK1; AEBP1; EMX2; MECOM; SCAND1; PIR; ID1; NKX3-1; RXRA; SSBP2; MNDA; ARNT2; NFATC4; TOX; TRIB3; KAT6B; ZSCAN18; ZIC1; SPDEF; FOXO4; CREB1
Down-regulation 95 CCNA2; MYCBP; HMGA2; MYBL2; FHL2; TCERG1; EZH2; PARP1; PTTG1; SUV39H1; FOXM1; BATF3; FOSL1; HDAC2; GTF2A2; DRAP1; NUP62; WHSC1; HMGB2; ETS1; HMGB1; BAZ1B; PPRC1; HMG20B; BCLAF1; CENPF; BRCA1; BMI1; SATB2; PA2G4; EED; NPM1; DNAJC2; EGR1; SMARCA5; AATF; RBM14; TFAM; ING2; UBE2I; CHAF1B; HMGA1; HNRNPD; RHOA; CTR9; RAN; XBP1; PSMC3IP; EGR3; CBFB; EGR4; BLM; TAF9; EDF1; ITGB3BP; NFKB1; SUB1; RNF4; HOXB7; RUVBL2; HOXC10; MYB; ECD; CEBPZ; C1D; SMARCE1; TRIM28; SFPQ; UBP1; ZBTB38; HLTF; SAP30; ALX1; C1QBP; CCNE1; BAZ1A; ILF2; MTF2; YWHAB; HMGB3; BHLHE40; TOX3; EGR2; SSRP1; TFDP1; KDM5D; CALR; MSX1; DNMT3B; JARID2; ETV1; IRF4; TSC22D2; HOXC6; PUF60