Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15969 Pelitinib GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 240 TSC22D3; PNRC1; ZNF611; NFE2L1; CALCOCO1; TRIM22; ZNF688; ZNF44; ZNF358; CERS4; HBP1; RELB; ATF3; HDAC5; ZMIZ1; IRF9; ZKSCAN4; ZNF160; YEATS2; PBX1; MKL1; CREBL2; ZNF532; PBXIP1; L3MBTL1; ZNF3; ELF3; ZNF467; EZH1; HMBOX1; NR5A1; ZBTB3; TFAP2A; SUPT7L; MNT; CDIP1; ZNF500; SREBF2; HDAC9; MEIS1; ZNF93; ZNF512B; EP300; FOXO3; ZNF701; FOXO1; ZNF669; ZNF224; ZNF208; E2F5; MED16; ZNF665; SALL2; RING1; MED12; ZNF33B; ZNF257; ZNF268; ZSCAN9; RSF1; BTG1; ID4; TEAD3; SOX12; ESRRA; CIR1; ZNF354A; SREBF1; HINFP; BCL6; ING4; ELF4; TAF7; BNC2; WNT4; PRDM14; TCF7; RFXANK; NAB1; KDM4A; ZNF117; MECP2; ZFHX3; CBFA2T2; TRIM29; DYRK1B; ZNF345; ATF4; ZNF140; AES; SOX4; ZNF135; ARID5A; TGIF2; ZNF721; SPIB; BCL3; ZNF573; TRIM16; CBX7; TSHZ2; SOX3; CSDC2; MEIS2; JUP; BCL11A; ZNF768; HOXD1; ZBTB44; ZNF667; ZBTB16; PHF20; ZNF623; HOXB5; ZSCAN31; ZNF131; MXI1; REL; TRIM24; ZNF112; BPTF; ZIC3; MXD4; ZNF423; LPIN2; ZNF350; PKNOX2; MZF1; ZNF239; HEY1; ID1; LOXL2; TFCP2L1; NHLH2; ZNF589; VGLL1; WWC1; ZMYND8; TCF7L1; SOX2; TWIST1; PEG3; MYCN; PCGF3; PRDM2; TP53; NFKB2; CEBPA; STAT2; ZSCAN18; FOXI1; TRPS1; CHD9; TLE2; ZKSCAN1; KLF3; ZNF85; BARX1; ZNF43; INSR; CUX1; NCOA1; NCOA2; LITAF; IRF7; ZNF415; BAZ2B; SIX3; TCEA1; RARB; ZNF91; TCF7L2; MYCL; RARG; ELF5; IRF6; TFEC; CUX2; OSR2; PIR; KLF11; TOX3; TOX; SMARCD3; LIN28A; FOXN3; ZNF652; HOXB6; DDIT3; PDLIM1; ERBB2; KAT2B; NR1H2; DBP; TCF4; ERBB4; TFDP2; SNAI2; MAF; SRCAP; ZHX2; ZFPM2; POU2AF1; HOXB2; EHF; ZNF195; ZBTB20; NFATC4; TCEA2; DLX5; TRIB3; TBL1X; EMX2; NFE2; SOX13; KLF5; AR; ESR1; TLE1; TP63; SSBP3; TFAP2C; KLF13; NPAS2; SCAND1; VPS72; ID3; TSC22D1; ARNT2; CBFA2T3; SSBP2; MYRF; WT1; BHLHE41; ARID5B; TAL1; ID2; GATA6; SPDEF; TLE4
Down-regulation 112 CCNA2; FHL2; HMGA2; MYBL2; SUV39H1; PARP1; EZH2; FOXM1; NPM1; TCERG1; TFAM; GTF2A2; RUVBL1; CHAF1B; MYCBP; WHSC1; HDAC2; BATF3; NUP62; ING3; HMGB1; BAZ1B; WDHD1; FOSL1; EED; BCLAF1; PA2G4; ZNF143; EGR1; SUB1; PSMC3IP; PTTG1; HSF2; NFKBIB; RBM14; RUVBL2; GABPB1; RAN; HMGB2; RHOA; CTR9; BMI1; CCDC59; TOPORS; RBL1; SFMBT1; TAF9; ITGB3BP; YEATS4; TRIM28; HNRNPD; SMARCA5; DRAP1; CENPF; SFPQ; PURA; BRCA1; SMAD5; DEK; EGR3; PIAS2; SATB2; HOXA1; ARNTL; BLM; MED1; EGR4; ING2; UBP1; RNF138; CRY1; RNF4; KLF2; TRRAP; BAZ1A; C1D; ELK3; CEBPZ; TSC22D2; CBX3; PTRF; FOXD1; TBPL1; CBFB; MBD2; ETS2; TFDP1; HLTF; ARNTL2; YWHAB; CCNE1; KDM5D; CCNC; MYB; ZBTB38; RBPMS; MYBL1; HOXC6; KLF6; NFIB; WWTR1; MSX1; E2F8; SAP30; MAGED1; SATB1; PBX3; NR2F2; TRIP6; NR2F1; ETV1; CREB1