Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15968 Pelitinib GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 216 TSC22D3; SUV39H1; NFKBIA; DAXX; ZNF467; PNRC1; ZNF611; BRF2; ZNF688; REPIN1; HDAC5; ZNF160; ZNF44; CARF; NFIL3; NCOA3; ZNF76; SPI1; E2F2; TRIM33; ZKSCAN4; MECP2; CBX7; ELF4; TBL1X; PHF20; BCL6; CDIP1; CDYL; DLX4; ZZZ3; ATF4; SOX3; HBP1; WNT4; IRF9; NR5A1; HINFP; AIP; ZBTB3; ELF3; VGLL1; KDM4A; KAT8; SRY; MKL1; TBX21; MNT; RSF1; ZNF721; TRIM24; GCM1; CBX4; ZNF701; CSDC2; TFEC; MEF2C; SIX1; PAX9; IRF1; RING1; PQBP1; FOXO3; ZNF573; ZSCAN16; PRDM2; RORC; ZMIZ1; CALCOCO1; SIAH2; THRB; BRD2; CEBPD; TRIM16; MXI1; TEAD3; NR3C1; SOX21; FOXA1; OSR2; GFI1; MED12; KLF3; NR1H3; PATZ1; SALL2; BRD4; ARID5A; TGIF2; TRIM22; CREB3L1; EPAS1; DYRK1B; LYL1; SOX4; RORA; CHD3; ZNF148; DDIT3; DDX17; ZNF75D; JUND; SAP18; JAK2; ZNF652; SP3; MXD4; RARA; TRIM29; ZNF33B; LHX3; RARG; ZKSCAN1; HSF1; ZNF350; BCL3; ZNF606; NFKB2; KAT2B; ZSCAN31; ERBB2; PDLIM1; IRF7; SRCAP; FOSL2; STAT4; XBP1; SETDB1; ZNF665; TLE2; EP300; ING4; ZNF239; ZBTB48; MITF; AES; CREB5; PBX1; ZBTB16; CAMTA2; ZMYM2; ZNF711; HDGF; MEIS1; TCF7L1; ZNF512B; ATF3; HOXD1; NFATC1; SOX13; PIR; OVOL2; LITAF; CITED2; IRF6; NCOA4; CEBPA; ZNF165; NKX2-1; ZHX2; FOXG1; TCF7; PLAGL1; NEUROD1; MAFB; ZNF91; SCAND1; ZBTB18; ERBB4; MYCL; TRPS1; NR1D2; NFE2; SOX10; HIRA; TCEA2; RFX5; HIPK1; KLF4; TRIB3; CTBP2; ELF5; BTG1; PAWR; CBFA2T3; SPIB; PEG3; ZNF217; CRYM; RXRA; KLF13; ESR1; KAT6B; TCF4; TCF7L2; AR; EMX2; ID2; ZFPM2; INSR; MNDA; OLIG2; SSBP2; AHR; FOXO4; TFAP2C; VPS72; BASP1; BCL11A; PITX1; HOXB2; PCGF2; RELB; ZIC1; GATA6; SNAI2
Down-regulation 98 CCNA2; MYBL2; HMGA2; EED; EZH2; TCERG1; FHL2; WHSC1; HMGB1; HDAC2; RUVBL1; PARP1; YEATS4; HSF2; FOXM1; FOSL1; CHAF1B; GMNN; MYCBP; NOC2L; BCLAF1; BRCA1; EGR1; DRAP1; NPM1; POLR3F; PURA; PA2G4; TFAM; TLE1; MTF2; LEF1; PSMC3IP; CBFB; PPARG; CDK8; BAZ1B; ETV4; RAN; TFCP2; RBBP4; RRN3; FOXC1; ECD; SUB1; NUP62; RHOA; CREG1; WWTR1; CENPF; MLXIP; BRD7; HOXA1; CEBPZ; NPAT; RUVBL2; ZFP36L2; SMAD3; CHD7; PRKDC; C1QBP; UBE2I; DNMT3B; CCNH; CDK2; TFDP1; RCOR1; CRY1; MED21; CTR9; ILF2; SATB2; TEAD4; RNF4; PTTG1; FOXD1; SOX9; TERF1; SSRP1; TRIM28; TULP4; HOXB7; HNRNPD; YWHAB; HMGB2; PTRF; ZNF232; NR2F1; NR4A2; ELK3; IKBKAP; TLE4; HOXC6; EGR3; ETV1; BHLHE41; CREB1; EGR2