Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15967 Pelitinib GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 239 TSC22D3; ELF3; TOX3; PNRC1; MKL1; ZNF611; ARHGAP35; PHF20; ZNF652; PATZ1; ATF3; REL; CALCOCO1; ZNF33B; ZNF688; SOX12; ZNF768; NCOA3; ZNF467; ZNF358; PBXIP1; MECP2; CARF; RSF1; ZNF160; BPTF; MAML1; TRIM29; ZNF224; NFAT5; KAT8; HDAC6; YEATS2; BTG1; HOXD1; ZBTB16; IRF9; TRIP11; HDAC5; ZKSCAN1; KDM4C; SREBF1; MNT; IRF6; NFATC3; HMBOX1; OSR2; NR5A1; PAX9; TRIM24; CREB5; FOXJ1; NFIL3; ZNF74; HOXC13; HBP1; HIF3A; ZNF165; NCOA1; HIVEP2; FOXK2; MLLT10; JUP; MYF5; TFEC; PBX1; HOXB3; NFE2L1; ZSCAN31; ZNF34; FOXN3; ZMIZ1; SETDB1; HSF4; CHD9; ZNF44; TCF25; HDAC9; MED15; WWC1; DDIT3; AES; MZF1; L3MBTL1; EHF; TERF2; BCL11A; NCOA2; EHMT2; NR4A3; CTBP2; ZNF257; ZNF264; ZNF124; ERBB4; FOXO3; ARID5A; TSHZ2; CDIP1; TEAD3; SRCAP; VGLL1; BCL6; BANP; TRPS1; HSF1; ZMYM2; TRIM16; MED14; ZNF589; ZFHX3; TFE3; RARG; SKI; PRPF6; LMCD1; ZNF117; MYCL; PRDM14; ZNF184; MEIS2; EP300; TP53; ATF4; ZNF623; KAT2B; CUX1; TLE2; TP63; CBX7; CBX4; CERS4; EZH1; ELF4; EMX2; FOXA1; KLF11; SOX3; GATA6; TGIF1; ZNF665; TBX1; OVOL2; ZNF711; ERBB2; GRHL2; ING4; CSDC2; FOSB; STAT2; CTBP1; JAK2; RCOR3; STAT3; MYCN; WNT4; HIRA; SKIL; KLF3; SALL2; THRA; PAWR; LITAF; TRIM22; PRDM2; PDLIM1; TXNIP; PSPC1; MEIS1; SMAD6; ARL2BP; HIC2; HIVEP1; IRF7; ZNF573; HOXB1; ZNF331; ZIC3; TLE1; ZNF721; JUND; ZNF512B; SP140L; FOSL2; SIX2; NR4A2; GLI2; MYRF; DACH1; EPAS1; TCF7; GTF2IRD1; CBFA2T3; SP110; EGR1; PIR; YAP1; ZNF195; CREB3L2; E2F5; MXI1; TBX3; PLAGL1; CEBPA; REPIN1; AR; HLF; SSBP3; FLNA; UBE2B; SOX2; NR1H3; HOXB5; SCAND1; ZNF91; TCEA2; TFDP2; TRIB3; TCF7L2; FOXO1; ESR1; ZNF423; RYBP; FOXF1; TWIST1; HOXB6; KLF5; GATA2; ARNT2; FOXC1; SPDEF; KLF9; SSBP2; HOXB2; TOX; TFAP2C; ARID5B; CRYM; NFATC4
Down-regulation 113 CCNA2; HMGA2; MYBL2; MYCBP; FHL2; NPM1; EZH2; HDAC2; PSMC3IP; PARP1; SUV39H1; FOXM1; MYC; RUVBL1; GTF2A2; GABPB1; TCERG1; PTTG1; HMGB2; FOSL1; EED; BCLAF1; HDAC1; HMGA1; RBM14; GMNN; DRAP1; BRCA1; CENPF; HMGB1; PA2G4; MTF2; BATF3; CTR9; TTF1; POLR3F; CCDC59; C1D; CREG1; TOPORS; ECD; PPARG; CHAF1B; NRIP1; HNRNPD; DEK; SUB1; BAZ1B; BMI1; CRY1; NUP62; EDF1; SSRP1; ING3; CHD7; RAN; RBL1; PREB; ETS1; RUVBL2; CBFB; DNAJC2; TFAM; SMARCE1; LEF1; SOX11; WDHD1; RHOA; TRIM28; RNF4; BAZ1A; TAF5; SFPQ; ELK3; ETV5; CBX3; TFDP1; ING2; NR3C2; ARNTL2; WWTR1; SHOX2; MTDH; IFI16; NELFB; MYBL1; ILF2; ZEB1; SAP30; PURA; CEBPZ; BLM; HHEX; TSC22D2; CCNC; YWHAB; AFF1; ZBTB38; IKBKAP; NR2F2; CNBP; NFIB; RREB1; BASP1; MYT1L; TRIP6; AEBP1; PUF60; MAFB; MSX1; ETV1; EGR2; HOXC6