Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15966 Pelitinib GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 217 TSC22D3; DMTF1; MNAT1; DAXX; ZSCAN16; GLI2; TEAD3; KDM4A; CALCOCO1; ELF4; HBP1; ZKSCAN4; HDAC6; PNRC1; ELF3; DLX4; JUP; BTG1; NFE2L1; EZH1; NCOA3; ARHGAP35; ZSCAN31; ZNF219; MLXIPL; MAFB; DLX5; ZNF446; IRF9; PIR; ZNF768; PBX1; ZBTB3; KAT2B; RSF1; SMAD6; TLE2; MZF1; EGR1; ZNF254; LMCD1; HOXC13; ZFHX3; ZNF224; PHIP; ATF3; ZMIZ2; ID4; ZNF358; ZNF84; ZNF467; ZNF444; PBXIP1; BAZ2B; NFATC3; NR4A1; ZNF12; ZNF688; TRIM22; APBB1; ZSCAN9; SIX1; MED14; RING1; ZNF345; ZBTB16; MEIS1; ERBB2; HR; RARG; EHMT2; DBP; CBX7; BCL6; DYRK1B; RFX5; EVX1; PHF1; SOX3; WNT4; ZNF532; IRF6; HTATIP2; ING4; CHD9; PAWR; ZNF33B; PRDM14; SOX18; HEY2; GRHL2; ZNF423; ZNF304; BPTF; ZNF611; TFE3; ZNF711; TRIM29; SRCAP; ERBB4; ZNF117; SKIL; ZNF175; CERS4; ZMYND8; ZNF226; L3MBTL1; IRF3; ZNF589; ZBTB44; OVOL2; ZKSCAN1; HMGN3; ZNF580; RNF10; TP63; ZNF75D; ZMIZ1; ZIC3; TBL1XR1; WWC1; KLF5; ST18; SMARCC2; MEOX1; VGLL1; ZMYM2; KLF3; TGIF1; MYCN; NCOA2; BRWD1; CIR1; ZNF248; PSPC1; ELF5; ZNF415; ZNF165; TULP3; BHLHE41; TBX1; FOXA1; MEIS2; BARX1; MXD4; TDP2; MECOM; ZNF205; HMBOX1; CBFA2T3; TRPS1; OSR2; DNAJC1; NFATC1; SOX2; MAF; BTAF1; CUX1; ZNF24; KLF11; SALL2; TCF7L1; RYBP; TOX; TCF4; IRF7; ESR1; KLF13; HDAC9; MYRF; ZNF195; FOSB; MYCL; EYA2; LOXL2; TOB1; PAX6; TCF15; CUX2; STAT3; TRIM16; PIAS3; SPIB; DLX2; ZBTB1; INSM1; TCEA2; TCF7; TOX3; ARID5B; AR; FOXO4; ZNF264; SSBP3; NR0B1; ID1; ARID4B; TSC22D1; TFDP2; FOXO1; TFEC; ZNF652; TXNIP; SOX17; MED13; GATA6; ZNF91; AEBP1; DACH1; HMG20B; BCL11A; ARNT2; WT1; ZSCAN18; SPDEF; TLE4; ID2
Down-regulation 132 MYC; CCNA2; ADRB2; MYCBP; RUVBL1; HMGA2; PPRC1; NPM1; GTF2A2; PARP1; HDAC2; MYBL2; FHL2; ATF6; FOSL1; NRIP1; TCERG1; REXO4; NFKB1; EZH2; MLX; ZBTB18; RAN; NOC2L; C1QBP; SUB1; DRAP1; RBL1; BCLAF1; XRCC6; SUV39H1; GABPB1; TFAM; ZFP36L2; BATF3; PA2G4; EED; THAP1; CEBPZ; ZBTB24; RNF138; WHSC1; TAF9; EDF1; SFMBT1; PITX2; HMGB1; ETV4; RBM14; PPARG; BRD3; SMAD1; TAF1A; PHF2; ING3; IFI16; RNF14; C1D; GCFC2; UBP1; TFDP1; CCNC; BAZ1A; TRIB3; HNRNPD; PSMC3IP; NUP62; ZNF593; TTF1; NPAT; HOXB7; RHOA; RNF4; ILF2; PURA; SFPQ; PREB; MYB; ZBED4; PRKDC; TEAD1; XBP1; SOX11; BRCA1; SSRP1; APEX1; ZEB1; MAFF; CTR9; HLF; ING2; RBPMS; KLF2; CTNNB1; NEDD8; HMGA1; CENPF; MAX; HES1; CITED1; FLI1; HMGB2; MYT1L; PMS1; PITX1; FOXD1; HIPK3; BLM; CEBPG; TBL1X; ENO1; SAP30; MAGED1; ZNF22; NR2F6; CBFB; HHEX; CNBP; KDM5D; CALR; ELK3; BMI1; YWHAB; PUF60; LEF1; SMARCA2; ETV1; SATB1; TCFL5; HOXB6; FOS; CREB1