Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15965 Azd-6482 GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 39 DMTF1; TAF1D; RNF138; NRBF2; ZSCAN16; TRIM27; ZNF24; MYBL1; HOXA10; TOX3; SMAD2; LPIN2; BRD4; EGR2; HMGB3; ZNF302; FOXA1; NR2F1; MYCL; BRD2; MTF2; CUX2; MEIS1; SPDEF; ASCL1; FOSB; ZNF189; DACH1; ZNF423; TAL1; LMCD1; MNDA; MYB; FOS; LEF1; WT1; TRPS1; TOX; CREB1
Down-regulation 29 ARNT2; TXNIP; TGFB1I1; USP16; CARM1; POU2AF1; CREG1; ZNF536; CNOT3; CALR; VPS72; SRCAP; ZNF580; KLF5; MAGED1; IRF8; RBPMS; MYT1L; ZBED2; TRIB3; PAX5; TGFB1; FLNA; ID3; MSX1; ZBTB38; HEY1; TRIM29; SATB1