Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15963	Azd-6482	GSE70138	MCF10A	Human	24h	1.11uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	57	GLI2; DMTF1; DAXX; MNAT1; TBX2; ZNF589; NFIL3; E2F2; TRIM33; TAF1D; AGO2; TSC22D3; WT1; HEY2; SIX1; PTTG1; SALL2; LITAF; SUB1; ZNF711; HMGB3; RNF4; NKX2-2; CDYL; CREB3L2; TOX3; ZNF32; ITGB3BP; TCF21; ZKSCAN7; NKX2-1; PEG3; BHLHE40; MYCN; ZBTB38; NAB1; BBX; BASP1; PMS1; ATF1; TGIF1; ZBTB1; NR0B1; HTATIP2; NR4A2; SOX11; MAFB; ATF3; IRX5; ZEB2; HMGN3; NFIB; CRYM; MAF; MEIS1; ASCL1; EGR3
Down-regulation	61	TFEB; MYBL2; SMARCD2; CARM1; PPARD; TWIST1; PRRX1; LEF1; FOXG1; HDAC9; NR1H2; FLNA; ZNF266; EYA2; ZEB1; ID1; MECOM; TCF7; STAT5B; TGFB1I1; SOX17; ZNF430; CEBPG; TXNIP; SLC2A4RG; POU2AF1; ZKSCAN1; ZFP36L1; AEBP1; HLX; HMGA1; NELFB; CNOT3; ELF3; MLXIP; JUND; NKX3-1; SSRP1; FOXO1; MEIS2; MED1; MYCL; TRIM28; IL16; PTRF; YAP1; PITX1; ZBTB18; MYRF; EGR1; PBX1; SMAD1; VPS72; TGFB1; TCF7L2; KLF2; EHF; BHLHE41; ZNF91; SATB1; NFATC4