Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15961 Azd-6482 GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 61 TSC22D3; TFAP2A; PNRC1; FOXO3; BPTF; NCOA2; CALCOCO1; ELF4; NCOR1; ATF3; IRF9; BTG1; SALL2; PBX1; ZNF589; WT1; TCF21; HMGB3; PCGF3; HBP1; HOXD1; TRIM29; KAT2B; CREG1; ZNF12; GLI2; FOXN3; SOX2; POU2AF1; SMARCD3; SMARCA1; MEIS1; ERBB2; BNC2; LITAF; AEBP1; FOXO1; CREB3L2; TCF7L1; ZNF217; IFI16; JUP; ZNF423; BHLHE40; MAF; KLF11; ZNF165; BCL11A; ARNT2; MEIS2; SNAI2; ZFPM2; SOX11; PBX3; TOX; ID3; PEG3; GATA6; BASP1; FOS; NFATC4
Down-regulation 42 MYBL2; STAT5B; EGR1; HMGA1; PSMC3; DRAP1; CAPN15; FOXJ3; TRIM28; PA2G4; TRIM25; LIMD1; FOXC1; HOXA10; MAX; RUVBL2; SIAH2; GTF2I; BMI1; ZBTB18; FOSL1; TXNIP; CBX6; AES; MED1; TGFB1; ASCL1; FLNA; CBFB; FOXG1; LEF1; BAZ1A; ZEB1; EGR3; SOX9; MYT1L; NFIB; CALR; ELK3; SATB1; ETV1; HOXC6