Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15960 Tgx-221 GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 60 WT1; IRF9; ATF3; HOXD1; ZFPM2; MEIS2; FOXF2; ZNF423; ZNF589; ID4; ZBTB20; HDAC9; TCF21; THAP7; ZEB1; MYCL; SALL2; PLAGL1; SMAD6; GTF2IRD1; TAL1; PKNOX2; JUN; HIRA; TWIST1; TOX; GATA2; TDP2; HOXB2; FOXF1; ZNF331; ZHX2; ZNF232; GATA6; BCL11A; TCF4; NFE2; MNDA; ID3; PBX1; IRF8; NR0B1; TRIB3; CREB3L2; JUP; KLF11; SOX17; THAP10; TCF7L2; HEY1; DACH1; ARNT2; HOXB6; NR2F6; TBX3; PBX3; MEIS1; PEG3; NFATC4; ID1
Down-regulation 32 RNF14; RBPJ; BMI1; ZNF107; KAT6A; SOX4; NPM1; MAGED1; CLOCK; FLNA; DNMT3B; ARNTL; RNF141; STAT5B; NCOR2; ENO1; BCLAF1; DDX5; GTF2I; BCL11B; RBPMS; EGR1; TXNIP; SMAD1; HOXC10; HOXC6; RFX5; BHLHE40; AFF1; ELK3; MAF; E2F2