Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15955 Tgx-221 GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 40 SUV39H1; SOX2; DAXX; PREB; KDM5D; PQBP1; SAP18; NFYB; NFE2L1; PIR; ZMIZ1; RUNX3; BATF3; TOX3; JARID2; MED24; SFPQ; JUNB; FOSB; SREBF1; NCOA6; ARNTL2; PHF20; TULP4; FOSL2; TP63; INSR; THAP11; ZBTB16; MYB; KLF9; IRF4; SAP30; PBX1; HOXC10; HOXC6; BHLHE41; AFF1; FOS; NR2F2
Down-regulation 62 ZSCAN9; NFE2; LYL1; ZNF85; MECP2; MEIS1; PNRC1; ZMYND11; CAMTA1; NR0B2; ZNF415; CLOCK; LOXL2; IRF7; ZFPM2; ZNF239; TGFB1; TP53; ZNF43; ZNF83; CHD9; UBE2I; TGFB1I1; WWC1; SP110; BAZ2B; SMARCD3; ZBTB20; ST18; ZKSCAN7; ZNF117; YBX1; MXI1; SOX11; IRF8; SOX17; SMARCA1; SMAD1; ZBED2; ZFP36L1; TCF4; ERBB4; TAL1; BCL11A; FOXF1; DACH1; CBFA2T3; MSX1; SOX9; LEF1; TXNIP; ID4; MAFB; ZNF91; VPS72; HOXB6; MEIS2; HOXB2; TLE4; NR2F1; MECOM; GATA6