Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15954 Azd-8330 GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 241 TSC22D3; SUV39H1; PNRC1; ADRB2; TRIM22; ELF3; CALCOCO1; PBXIP1; GLI2; CDIP1; NCOA3; CREBL2; NR5A1; ZBTB3; CEBPD; ELF4; IRF9; BTG1; HBP1; ZNF136; ZNF611; ZNF688; OSR2; ID4; ETV2; FOXD3; SOX3; SOX4; ARNT; ZNF224; BNC2; ZSCAN31; ZNF33B; SREBF2; ZKSCAN4; FOSL2; ZNF257; DYRK1B; WNT4; FOXO3; ZNF350; SALL2; MAML3; MNT; ZNF345; MEIS1; ZNF701; ZBTB16; HIF3A; IRF6; RSF1; ZNF112; DLX4; MKL1; SMARCA1; CEBPZ; TAF6L; ZNF225; HDAC5; LDB1; TRIM29; CARF; ZNF573; PQBP1; SUPT7L; ZNF512B; RORA; NCOA1; THRB; AFF2; BPTF; TEAD3; PRDM2; TAF7; CSDC2; EPAS1; ZKSCAN1; MXI1; ZNF426; MED12; LZTR1; MEIS2; ZNF652; MITF; ATF3; TCF7L1; HDAC9; VENTX; ZNF589; FOXF2; FEZF2; ID2; ZBTB44; TRIM16; FOXN3; PBX1; ZNF12; ING4; ZNF44; ZMIZ1; ZNF268; BBX; VGLL1; SKIL; MEOX1; ZNF223; PAWR; SIX3; FOXJ1; ZNF667; ZNF768; NFKB2; BCL6; NR1H2; PIAS1; TBX1; ZNF544; SRCAP; ZNF160; AES; TRIM24; ERBB4; PFDN5; CUX2; YAP1; TSG101; TCF21; ZNF75D; CERS4; NCOA2; ERBB2; HOXB1; REPIN1; SIM1; IFI16; ZIC3; KAT2B; CBX4; JUP; PEG3; NFE2L1; ZNF623; MYCN; TFDP2; PEX14; ZNF394; GATA6; ZNF91; SP110; ZNF165; SMAD6; ZNF264; NEUROD1; TFAP2C; SETDB1; MEOX2; ZNF711; LIN28A; ZNF665; SMARCC2; E2F5; LITAF; NR1H3; ZBTB20; BCOR; TERF1; ZNF606; PLAGL1; HTATIP2; CUX1; TXNIP; KLF13; NR1H4; WWC1; PITX2; KLF3; REL; STAT6; TOX3; NR5A2; ZNF331; TFCP2L1; PHIP; TRIB3; HEY1; MYCL; ID3; TCF7L2; ESRRG; TLE1; SNAI2; TP63; TFEC; PDLIM1; HOXD1; SOX2; RARG; TBX3; SSBP2; ZHX2; HLF; TGIF1; MAF; CITED2; KDM5D; PPARGC1A; IRF1; NR1D2; SMARCD3; KLF5; CREB3L2; TOX; HIPK1; ZBTB1; CREM; SOX13; BCL11A; FOXO1; TULP3; ZFP36L2; ZNF423; TRPS1; TCEA2; FOXF1; MED13; AR; BACH2; MECOM; CREG1; KAT6B; ZSCAN18; TCF4; ARNT2; TLE4; FOXO4; ZIC1; TWIST1; ARID5B; ID1; CREB1; NFATC4
Down-regulation 91 CCNA2; WHSC1; EZH2; FOSL1; HMGA2; MYBL2; HMGB2; PARP1; TCERG1; FOXM1; CENPF; HMGB1; NFKBIB; DRAP1; CHAF1B; HMGA1; PSMC3IP; NUP62; BAZ1B; BATF3; PTTG1; TBP; EGR1; HLTF; RBM14; SATB2; BRCA1; RNF138; EED; SMARCE1; HSF2; RAN; SMARCA4; WDHD1; HNRNPD; NFKB1; HOXA1; PA2G4; XRCC6; SMARCA5; BLM; BMI1; NPM1; PURA; DNAJC1; PRKDC; ETS1; CBX5; SF1; TAF1A; CHD7; BCLAF1; ITGB3BP; TRIM28; KMT2A; SNW1; GATAD2A; EDF1; MTDH; NELFB; CRY1; PAXBP1; PSIP1; RBBP4; SSRP1; HOXB7; RNF4; YWHAB; RUVBL2; ILF2; KLF2; EGR3; ENO1; CBFB; MED1; TFDP1; POU4F1; ELK3; HOXC10; ARNTL2; MSX1; VDR; SAP30; HOXC6; NKX2-2; IRX5; NKX3-1; ETV1; BASP1; SOX9; SATB1