Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15953	Azd-8330	GSE70138	MCF10A	Human	24h	0.12uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	DMTF1; TSC22D3; SUV39H1; ARID5A; PNRC1; HBP1; ZNF721; NFKBIA; ZNF611; TRIM22; DLX4; SOX4; PHF20; ZNF160; MKL1; ZBTB16; NFIL3; PBXIP1; ADRB2; SREBF2; CALCOCO1; BAZ2B; TRIM24; ZKSCAN4; PDLIM1; ZNF33B; ZNF44; ELF4; CREBL2; SP110; ZNF688; JUP; ELF3; NR5A1; NFE2L2; CEBPD; COPS2; ZBED1; BCL6; SIRT7; HDAC5; HTATIP2; ZMYM2; WNT4; ZNF224; NCOA2; EPAS1; ZSCAN31; ZNF467; TFEC; PFDN5; FOSL2; TFE3; CSDC2; TLE1; TRIM29; FOXJ3; FOXO3; SRCAP; TRIM16; TRAK1; KAT2B; ATF3; SALL2; DDX17; OSR2; IRF9; MAF; HDAC9; SREBF1; NCOA4; PQBP1; ZKSCAN1; IRF6; HSBP1; MITF; CUX2; MEIS1; ZNF652; TOX; ZBTB20; ZNF268; NR1H3; GLI2; AES; NAB1; PHIP; PLAGL1; CEBPA; SNAI2; KLF3; MYCN; REPIN1; MXI1; SP140L; MKL2; PAWR; TOX3; CHD9; SOX13; LITAF; ZNF165; ZBTB1; AHR; RUNX1; FOXF2; TBX3; TRPS1; CREM; NKX2-1; ZIC1; HMGN3; VGLL4; PIR; PPARGC1A; CREG1; TWIST1; ID2; FOXO4; GATA6; ZNF91
Down-regulation	99	CCNA2; MYBL2; FOXM1; HMGB2; TCERG1; EZH2; FOSL1; CENPF; WHSC1; CHAF1B; ETS1; RNF138; PTTG1; CCDC59; PPARG; EGR1; WDHD1; TFAM; YEATS4; PSMC3IP; NFKBIB; HSF2; HMGB1; ETV4; TAF9B; BRCA1; SMARCA4; SATB2; BAZ1B; ILF2; ZMYND11; C1QBP; TTF1; NPM1; CDK8; HMGA1; SMARCA5; PSMC3; KMT5A; CBX5; NUP62; DEK; DRAP1; RAN; MED1; CHD7; TAF1A; CREB3L1; GATAD2A; RBM14; SSRP1; FOXD1; CRY1; ITGB3BP; WWTR1; LEF1; UBE2I; HOXB7; PA2G4; PLAGL2; SUB1; RAD21; BLM; TRIM28; BCLAF1; MYB; PURA; SMAD3; HNRNPD; TEAD4; WT1; KLF6; ZFP36L1; PSIP1; EGR3; YWHAB; RBBP8; KLF10; CDK2; SMAD1; ING2; SOX11; TFDP1; KLF2; ETV1; SAP30; IRF4; SOX9; ZBTB18; MSX1; NKX3-1; MYT1L; FOS; EGR2; ELK3; SATB1; KDM5D; BHLHE41; CREB1