Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15952	Azd-8330	GSE70138	MCF10A	Human	24h	0.37uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	TSC22D3; ADRB2; PNRC1; KDM5B; SOX4; PHF20; MKL1; CALCOCO1; GATA3; SREBF2; NFE2L1; ARNT; ZNF768; ELF3; TRIM16; CREBL2; ZNF688; ZSCAN31; TRIM22; ZFHX3; BRCA1; ZNF160; ZNF44; ATF3; KDM5A; JUP; ARID5A; ZNF536; ID2; ZNF611; ZKSCAN1; AES; SOX12; DYRK1B; PDLIM1; IRF6; MXD4; CEBPD; BBX; BAZ2B; BPTF; LDB1; PBXIP1; MNT; HIVEP2; HBP1; L3MBTL1; ELF4; FOXK2; FOXJ1; STAT5A; EPAS1; STAT2; HDAC9; MXI1; SP110; ZNF646; ERBB2; CERS6; HDAC5; FOXO3; ZNF652; HMBOX1; IRF9; TRIM24; KLF5; MYCN; E2F5; HOXB2; ID1; TRIM29; EP300; ZNF665; SREBF1; RFX5; TOX3; STAT3; REPIN1; FOSL2; TFDP2; JUN; EHF; ZNF711; SRCAP; HDAC7; CDYL; BTG1; TLE1; HOXB6; ID3; VDR; TOB1; INSR; FOXN3; MEIS1; FOSB; SIX2; VPS72; SERTAD2; SNAI2; ZNF423; SMAD6; PAWR; TWIST1; ZIC1; RUNX1; AHR; FOXO4; CTBP2; CUX1; CBFA2T3; MYCL; KLF4; MNDA; TXNIP; VGLL4; JARID2; BCL6; MECOM; MYB; HMGN3; IRF1; TCF4; CREG1; SMAD7; RXRA; ZNF91; TOX; EMX2; SSBP2; GATA6; MAF; FOS; ARID5B; CREB1
Down-regulation	88	CCNA2; FOXM1; NFKBIA; MYBL2; HMGA2; EZH2; FOSL1; TCERG1; PTTG1; HOXA5; SUV39H1; HMGB2; PARP1; CENPF; EED; BCLAF1; FHL2; WHSC1; ETS1; GMNN; WWTR1; CHAF1B; ETV4; EGR1; YEATS4; CCDC59; HOXA1; KMT5A; NPM1; RNF4; TFAM; DNMT1; SUB1; HMGA1; SATB2; HMGB1; EGR4; RBBP8; HSF2; SALL1; C1QBP; PA2G4; NFKB1; CAPN15; DRAP1; USP16; PAXBP1; ILF2; NRIP1; PREB; PURA; RAD21; CRY1; BATF3; PGR; ING3; TRIM28; RAN; NFIB; CBFB; SSRP1; CEBPZ; RBPMS; HHEX; EGR3; ZNF211; SOX10; HNRNPD; BIRC2; MAFF; ETV5; HLTF; BMI1; MYBL1; PBX3; CCNC; ZNF22; NKX2-2; CHD7; FOXG1; PAX6; ETV1; CITED1; TSC22D2; EGR2; NR2F6; CDK2; SATB1