Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15951 Azd-8330 GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 246 TSC22D3; ZKSCAN4; PNRC1; ADRB2; ELF4; ZNF688; CALCOCO1; TOX3; NCOA3; GLI2; CDIP1; ZNF467; NCOA2; ZNF44; ZNF669; ZBTB16; HMBOX1; NR5A1; ZNF611; RING1; NFKBIA; TRIM29; MEIS1; INSM1; WNT4; TFAP2A; ZNF33B; HDAC9; MECP2; ATF3; FOXF2; SALL2; HINFP; TBX4; TRIM24; ELF3; ARNT; ZNF500; YEATS2; BNC2; ZBTB3; REL; LZTR1; CERS4; HIF3A; SOX4; HESX1; PEX2; IRF9; MKL1; ZNF652; SOX3; ZNF665; ZNF93; TEAD3; MEIS2; ZNF160; NFKB2; AFF2; NR0B2; ZSCAN31; SRCAP; ATOH1; ZNF701; CREBL2; FOXO3; CARF; PBXIP1; SPI1; ZNF345; EPAS1; BTG1; IRF6; ING4; OSR2; ZNF219; JUP; SUPT7L; HBP1; HOXD1; HDAC5; SREBF1; TFDP2; MZF1; ZNF140; ZNF606; TSHZ2; CUX2; ZNF224; DYRK1B; ZSCAN9; ZFPM2; ZNF536; ZMIZ1; VENTX; CSDC2; L3MBTL1; ZNF667; ZNF654; ZNF573; NCOR2; ZFHX3; BAZ2B; PDLIM1; ZBTB44; ARID5A; STAT5A; ZNF223; OVOL2; NFIL3; SIM1; ZNF512B; TBX1; ZKSCAN1; HOXB13; AES; CCNH; TOX4; ZNF124; GLI1; BRD4; PRDM12; ZNF112; MNT; ZNF589; ZNF544; KLF13; THRB; THAP7; FOSL2; HOXB1; LITAF; BARX1; STAT2; ID2; VGLL1; SMARCD3; ZIC3; ZNF268; MYCL; ZNF91; TRIM22; PLAG1; MYRF; PIR; CUX1; TERF1; CBX7; TXNIP; STAT3; ZNF415; RORC; ZNF85; CHD8; SOX2; MXD4; ZFHX4; NFE2L1; BCL11A; GATA6; ZNF671; ZNF264; ID4; NEUROD1; SMAD6; KLF5; NFATC4; TLE2; ZNF32; BCL6; FOXN3; MXI1; KLF3; IRF7; ZNF711; ZNF350; PLAGL1; RARG; TFEC; TCEA2; ASCL1; TWIST1; ZNF423; TGIF2; PHF20; MKL2; JUND; FOXA2; ZNF117; ZHX2; CHD9; PEG3; MAF; CBFA2T3; ZNF12; MITF; ZNF43; DLX5; ZNF131; EMX2; HIC2; NFIC; AHR; HDAC4; FOXF1; ERBB4; IRF1; ST18; HIRA; TCF7L2; MYCN; INSR; VPS72; SNAI2; ZIC1; ERBB2; PAWR; ZNF232; SOX13; TRIM16; TULP3; TRIB3; ID1; AR; TP63; TCF7L1; CREB3L2; SOX17; ZSCAN18; FOXO4; HEY1; ARNT2; ZNF165; SSBP2; VGLL4; TOX; KAT6B; DACH1; MECOM; HMGN3; ARID5B; WT1; HOXB2; TRPS1; TFAP2C; TBX2
Down-regulation 111 CCNA2; HMGA2; MYBL2; FOXM1; HMGB2; BAZ1B; EZH2; CENPF; FHL2; PARP1; HMGB1; PTTG1; TCERG1; FOSL1; PSMC3IP; EED; DNAJC2; WHSC1; CHAF1B; SUV39H1; DRAP1; BCLAF1; DEK; EGR1; TRRAP; RBM14; CCDC59; HMGA1; CBFB; BRCA1; TFAM; NPM1; ITGB3BP; CREG1; BLM; SMARCE1; IKZF5; PSIP1; RNF138; RBL1; HSF2; DDX54; ING3; CBX5; HOXC6; HNRNPD; EGR4; SMARCA5; CHD7; TAF5; SUB1; WDHD1; PA2G4; TTF1; UBP1; KLF2; GATA3; NUP62; SAFB2; HOXC10; PURA; TBPL1; CTR9; ZNF107; BRD3; EGR3; CEBPZ; SMAD3; EDF1; STAT1; BAZ1A; SATB2; UBE2I; RNF4; RHOA; MED1; TULP4; BMI1; TFDP1; SSRP1; HLTF; WWTR1; NFIB; CITED2; NR4A2; BHLHE40; ING2; RBPMS; ELK3; PITX1; HOXB7; NKX3-1; CCNE1; MYB; MYBL1; NR2F2; BASP1; JARID2; CALR; EGR2; SMAD1; TRIP6; ZEB2; CDK2; KDM5D; SAP30; SOX11; ETV1; NR2F1; MSX1; GATA2