Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15950	Azd-8330	GSE70138	MCF10A	Human	24h	3.33uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	TSC22D3; ZSCAN31; ESR1; ZNF688; PNRC1; MEIS1; WT1; IRF7; PEG3; NFKBIA; SOX17; SOX12; ZKSCAN4; ATF3; TRIM24; TRIM22; GCM1; GATA3; PDLIM1; WNT4; OSR2; NR2C1; HDAC5; NR5A1; SIRT7; IRF9; SOX4; TEAD3; ZNF516; ZNF467; HAND1; ZNF611; ELF4; ERBB4; ZNF44; PBXIP1; CSDC2; TOX3; CEBPD; ID2; ELF3; TRIM16; BTG1; FOSL2; PHF20; FOXO3; PRDM12; CERS4; SALL2; ZNF768; ERBB2; EYA2; TCF25; RUNX1; SIAH2; NHLH2; ZNF415; SSBP2; SMARCA1; OVOL2; MXI1; LPIN2; ZNF160; SMAD6; HBP1; ZNF423; SOHLH2; SETDB1; STAT2; MYCN; AHR; ZNF205; TFEC; E2F5; EP300; BPTF; MAF; SP110; ING4; PEX2; HOXB6; ZNF652; JUND; HMBOX1; IRF6; HOXD1; HEY1; HOXB5; ZFPM2; SIX1; CREBL2; MXD4; TLE1; SCAND1; TRIM29; NCOA2; TCF7; GATA6; TRPS1; RFX5; SRCAP; ZBTB16; HOXB2; BNC2; SNAI2; HMGN3; MEIS2; MNDA; DLX5; PIR; ST18; LMCD1; TGIF1; ZIC1; JUN; JUP; CD3D; TOB1; CTNNB1; VPS72; EMX2; CUX1; HLF; TOX; HSBP1; TFDP2; APEX1; ASCL1; SOX2; IRX5; ZNF165; BCL6; AR; TCF4; MYRF; DACH1; ID4; TSC22D1; MEOX2; FOXG1; CREG1; FOXO4; SPDEF; ZBTB18; MECOM
Down-regulation	110	CCNA2; MYBL2; HMGA2; FOXM1; EZH2; HMGB2; ABL1; SMARCA4; PTTG1; TCERG1; CENPF; GMNN; HMGB1; PARP1; WHSC1; EED; TOPORS; SMARCA5; NFKBIB; SUV39H1; RUVBL1; EGR1; PPARG; FOSL1; TFAM; BRCA1; ING3; ETS1; BAZ1B; PA2G4; PURA; PPRC1; HOXA1; RBM14; HNRNPD; DEK; SSRP1; HSF2; CBX5; MTF2; ETV4; BCLAF1; BRPF1; NRIP1; PSIP1; PSMC3IP; YEATS4; EDF1; NELFB; HMGA1; GABPA; BATF3; TFEB; KMT5A; CARM1; TTF1; CBFB; RUVBL2; SMAD3; CAPN15; NPM1; C1QBP; MYBL1; GATAD2A; STAT1; BLM; BMI1; SIM2; SATB2; TGFB1; UBE2I; ALX1; DNAJC2; PSMC3; RNF4; TRIM28; TRIP6; MLXIP; URI1; FOXD1; CEBPZ; CEBPG; HLTF; CNOT3; WWTR1; EGR2; NR4A1; CHD7; NFIB; CHD1; TSC22D2; TFDP1; ZBTB38; CDK2; KLF9; CREB3L2; RERE; PBX3; EGR3; PTRF; FOXC1; HOXC10; NFE2L3; YWHAB; KDM5D; CREB1; NR2F2; AFF1; ELK3; ETV1