Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15949	Azd-8330	GSE70138	MCF10A	Human	24h	10uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	131	TSC22D3; NFKBIA; NCOA3; ELF3; PNRC1; TRIM22; ATF3; TRIM29; HBP1; JUP; SREBF2; SOX4; ID1; ADRB2; ZNF611; CREBL2; MKL1; TRIM16; ZNF160; ZFHX3; ZNF33B; ZSCAN31; FOXO3; FOSB; BPTF; PLAG1; ZNF721; IRF6; RSF1; IRF7; GATA3; CALCOCO1; HIVEP1; MEIS1; L3MBTL1; KLF5; NR3C1; ZNF44; HIVEP2; ID2; MXD4; IRF9; ZNF768; NCOA2; SP110; BTG1; SIM1; NCOR2; ZNF331; PDLIM1; HTATIP2; ERBB2; PBXIP1; ZMYM2; ZNF667; ZNF665; TLE1; TSG101; AES; CBX7; NR2C1; TOX3; HDAC5; STAT1; SOX3; OSR2; WNT4; EP300; ID3; PIR; OVOL2; ZBTB16; TFEC; MYCL; ING4; TP53; NFAT5; PHF20; ZBTB43; CUX1; SRCAP; ZSCAN18; GRHL2; ETV1; TLE2; LIN28A; BCL11A; KLF4; SREBF1; PBX1; BCL6; SALL2; KLF9; SMAD6; STAT3; BNC2; PEG3; ZNF512B; FOXN3; TFAP2C; TBX3; ETS2; SP100; FOXF1; FOSL2; PPARGC1A; BCL3; KLF6; HSBP1; HEY1; AHR; NANOG; SMARCD3; MAF; SATB1; ID4; VGLL4; ZNF165; EMX2; ZNF652; TSC22D1; ELF1; NR4A2; SCAND1; ISL1; EHF; TWIST1; TCF4; ASCL1; GATA6; ZFPM2
Down-regulation	99	CCNA2; MYBL2; FOXM1; HMGA2; HMGB2; FOSL1; EZH2; SUV39H1; GMNN; TFAM; DEK; CHAF1B; PSMC3IP; DNMT1; CENPF; PARP1; RNF138; WHSC1; HDAC2; RBL1; CBX5; PTTG1; HMGB1; EED; YEATS4; BAZ1B; TAF9; NPM1; PA2G4; BCLAF1; TOPORS; DNAJC2; BATF3; EGR1; MYBL1; ZFP36L1; WDR77; ING3; NRIP1; WWTR1; HNRNPD; CCDC59; RBM14; DRAP1; ING2; WDHD1; EGR4; PPARG; RFC1; BAZ1A; ZNF146; RBBP8; HOXA1; BRCA1; CBFB; SAP30; ITGB3BP; CRY1; HOXD10; RAD21; TBL1X; ZNF410; RUVBL2; NUP62; BLM; BMI1; CEBPZ; CEBPG; PURA; TRIM28; HLTF; HOXD11; HDGF; SSRP1; HOXC10; NKX2-2; EGR3; BASP1; TFDP1; HHEX; HMGA1; TGFB1; POU2AF1; ZBED2; BRIP1; WT1; NFIB; SATB2; PAX6; ELK3; PAX5; NKX3-1; TRIP6; EGR2; NR2F1; ZBTB18; CREB1; HOXC6; KDM5D