Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15946 Ldn-193189 GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 77 SOX2; POU2AF1; LIN28A; ZMYM2; DLX4; TRIM24; PRRX1; ERG; NKX2-1; GFI1; POU5F1B; MYB; TFDP2; PRDM14; ZNF654; FOXF2; TOB1; ZNF107; TAF11; ZBTB16; TBL1X; DLX5; KLF1; DLX2; LEF1; ZNF532; NANOG; TRIM22; ZEB1; ZNF160; NFE2L1; FOSB; ZNF239; NFE2; HMGB2; HMGB1; ZNF165; ZNF423; ZIC3; HIC2; TBL1XR1; AEBP1; NR4A1; SALL1; EGR1; CTR9; WNT4; PIR; ZSCAN18; TCF7L1; RNF6; TWIST1; CBFA2T3; STAT3; ZNF117; KLF10; DACH1; SSBP3; EYA1; PBX3; CTBP2; TCF4; OSR2; TAL1; WWTR1; FOS; CRYM; ID1; HOXC10; ARNT2; AFF1; KLF4; ID3; HOXB2; MAFB; EGR2; HOXC6
Down-regulation 45 PPARD; KAT5; NFKBIA; PUF60; KAT8; SOX4; ZNF629; CARHSP1; FOXC1; HMGA1; APEX1; PLAGL1; ERF; HSF1; ETS2; BRD4; ZNF468; MED24; CEBPB; SP110; ZNF623; NAB1; MED1; MEIS1; RBBP7; TSC22D1; SOX9; BMI1; BCL6; ELK3; EMX2; PDLIM1; NR2F2; LITAF; ID2; MECOM; NFIB; BHLHE40; WT1; KLF2; MEIS2; BCL11A; PCGF2; KDM5D; GATA2