Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15945 Ldn-193189 GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 60 NFIL3; TSC22D3; NR1H2; PNRC1; CEBPD; FOXO3; TAF1D; TP53; ZBTB16; ZSCAN16; CREBZF; THAP11; FOXJ3; ZNF33B; ECD; ZNF226; ZNF529; MED12; HOXC6; FOXO1; BRD8; RFX5; LPIN2; SMARCD2; PSPC1; SP2; DEAF1; CEBPZ; HOXB7; AEBP1; HOXC4; STAT1; BRD4; BTG1; NR4A1; ZNF227; RORA; SIAH2; POU2AF1; RUNX3; CITED2; POU4F1; PIR; MED17; TRIM22; VDR; MAZ; HOXC10; SOX10; ZBTB1; IRF4; TBL1XR1; MXI1; BACH2; OSR2; TCF3; LEF1; NR4A2; CRYM; ELF1
Down-regulation 47 LOXL2; EGR1; HMGA2; BRPF1; GTF2IRD1; SOX9; TFEB; DRAP1; TADA3; PITX1; MNDA; NAB1; CEBPB; CREM; FOXF1; DACH1; BHLHE40; BMI1; MAFF; FOSL1; MYRF; VPS72; ST18; PBX1; ZNF117; ZNF91; PTRF; RUNX1; CALR; ATF3; SNAI2; HHEX; TSC22D1; BCL3; ISL1; SMAD7; NR2F6; SATB1; MEIS2; TBX3; ID1; BASP1; EGR3; ID2; ELK3; GATA2; KDM5D