Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15944 Ldn-193189 GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 99 PPARG; ATF3; NCOA3; PAX8; NFKBIA; NR4A1; ATF6; FOSB; GABPB1; TSC22D3; MAFG; STAT1; NFE2L1; PNRC1; PCBD1; FOS; MITF; HBP1; HMBOX1; IRF7; NFKB2; JUNB; EGR1; BBX; BRD4; ZBTB43; ELF4; NR4A2; BTG1; ZKSCAN1; CALCOCO1; MXI1; RCOR3; HIVEP1; HTATIP2; NKX2-1; DDIT3; FOXO3; KLF5; ZNF160; TRIM22; TGFB1I1; IRF9; FOXF1; XBP1; PEX14; HOXD1; REL; NR4A3; SMAD2; MAFF; TSG101; FOXF2; PHIP; BASP1; TRIM29; HIC2; TFDP2; MED13; PSPC1; TCF7; FOSL2; TBX3; PIR; JUP; KLF7; NRBF2; ZNF117; SP100; ARID4B; SRCAP; ZNF165; RELB; TSC22D1; UBE2B; BRCA1; TRIM16; TGIF1; ZBTB16; TRIB3; JUN; ST18; BCL6; EGR3; ERBB4; ELF5; ZSCAN18; KLF11; FOXO1; RYBP; CUX1; MECOM; FLNA; HEY1; TLE4; BHLHE41; ZNF91; EGR2; CREB1
Down-regulation 76 CCNA2; MYBL2; MYCBP; EZH2; FOXM1; GMNN; ADRB2; HOXA5; YEATS4; CBX5; HMGB1; PA2G4; HMGB2; PRKDC; CHAF1B; SUV39H1; HOXC4; DEK; SLC2A4RG; TFAM; WWTR1; BMI1; C1QBP; CRY1; NUP62; SUB1; ATF5; RBL1; SMARCD2; TFDP1; DEAF1; ERCC2; TAF9B; CARHSP1; HLTF; RBBP4; TFCP2; HNRNPD; APEX1; CTR9; ETV5; RNF141; EYA2; BLM; MED24; PTTG1; ILF2; NR2F1; CBFB; RBBP8; NFIB; PIAS3; TRIM28; HOXC6; ELK3; IL16; PBX1; NKX2-2; HES1; MAFB; ZNF22; PCGF2; TWIST1; ZFP36L2; IRX5; NR0B1; VGLL4; AEBP1; ETV1; ID2; MEIS1; ASCL1; CDK2; PBX3; NR2F2; IKZF1