Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15941 Cgp-60474 GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 656 NFKBIB; BRD4; TSC22D3; RFX1; HOXD3; SUV39H1; CDIP1; GMEB2; SOX2; WT1; ZNF136; ELF4; TAF1C; ZNF34; ZNF79; MLLT1; ZBTB3; ZKSCAN4; KAT8; ZNF573; ALX4; PRDM2; EMX1; SOX14; DOT1L; HINFP; ZNF529; ATF3; SCRT1; NCOA3; IRF9; ETV2; ZNF442; RFX3; DLX4; ZNF667; L3MBTL1; DCC; DLX2; NEUROG3; SNAPC4; GCM1; HOXD1; FOXH1; TEF; E4F1; NEUROG2; SPI1; NHLH1; ZNF549; EP300; ZNF345; TP73; HOXB8; ZXDB; PAX7; ZNF701; POU6F2; CBFA2T2; HIC2; POU3F2; PAX3; SOX21; ZNF668; SOX3; POU3F4; NR1I3; VGLL1; FEZF2; GLI2; VENTX; ZNF16; POU4F3; PRDM16; NR5A1; ZNF460; ZNF749; CIR1; POU3F3; PROX1; UTF1; CUX2; MAML3; CBX2; ST18; ZNF606; ZNF440; ZBTB44; ZNF263; ZNF623; ID4; CDX1; ZNF142; ZIC4; ZXDC; CSDC2; LYL1; ZNF362; FOXD3; ZNF408; MNT; ASCL2; ZNF334; FOXE3; SRY; ZNF350; ZNF225; ZNF7; ZNF550; ZNF682; ZNF471; ZNF589; DLX6; PRDM9; ATOH1; DYRK1B; ERBB4; FOXB1; TULP1; PEG3; ZNF500; TAF4B; ZNF174; ZNF787; HES2; GBX2; ZNF778; MYCL; GSC2; ZNF304; MAFG; SOX1; ZNF81; ZNF780B; ZNF814; TULP2; CEBPD; THRA; RBPJL; KLF13; ZNF80; ZNF222; ZNF432; HDAC9; ZNF221; HOXD12; VHL; PEX14; MAFK; ZNF3; HOXA6; ETV3; MECP2; TBX1; PROP1; ONECUT1; ZNF407; CARF; HNF4A; CRX; HNF4G; LBX1; ZNF674; CIITA; HOXB1; GFI1; TGIF2; HESX1; THRB; ZNF695; NEUROD4; ZNF132; FOXL1; DMRT1; PRDM12; PKNOX1; ZNF214; POU2F3; SNAI1; NOCT; ZBTB7B; ZIM2; MYF5; ZNF444; NR6A1; MYNN; ZNF257; NKX2-5; AFF3; HSF1; ZSCAN16; HLX; NEUROD1; ZNF157; ZNF254; SP2; PPARA; KMT2D; ZNF112; IKZF3; CDX4; ZNF235; BRF2; ZNF41; NR1I2; CHD2; EZH1; ZNF14; ZNF343; GCM2; HOXD13; MYRF; NANOG; ESRRB; PAX4; NFE2L2; TBR1; CBX4; ZNF44; HIC1; DACH1; SIX6; PRRX1; BRDT; DAXX; ZNF117; TBL1Y; TLX3; GMEB1; HDAC5; ZNF506; ZNF764; VAX2; ZNF391; POU1F1; ZKSCAN8; NHLH2; HNF1B; TCF21; ZBTB16; WNT4; NAB2; ZNF492; ZNF771; TAF5L; ZNF155; TAF6L; AIRE; ZNF223; POU6F1; NR4A3; ARHGAP35; CALCOCO1; BNC1; NR2E1; SP4; MAPK8IP1; ZNF74; PRDM14; ZNF613; GRIP1; SIN3B; LMX1B; LIN28A; PAX1; HIF3A; MSX2; HHEX; THAP9; MEIS2; ZNF426; IKZF2; MBD1; ATF6B; NFKB2; ZNF131; ASCL3; TFAP2B; NPAS1; SALL2; TBX4; OVOL1; TRIM24; ZNF331; ZNF324; PITX3; ZSCAN2; ZNF629; ZNF177; NEUROD2; HIRA; MYEF2; E2F1; ZNF688; ZBTB32; TBX6; ZNF264; NEUROG1; TDP2; SOX5; LHX3; LDB1; ZNF813; ZNF93; CERS4; MED12; ZBTB17; MEOX1; PNRC1; MNDA; ZNF675; SIX3; ZNF556; ERF; MZF1; SOX18; ZNF274; SSX7; ZNF654; ONECUT2; SCAI; ZNF12; ZNF510; PPARD; RORB; TRIM22; SMAD6; ZNF467; RARG; TBX5; NFIX; ZNF10; HABP4; ZNF234; SOX12; TFAP2A; TLX2; ZNF512B; ACTL6B; ZFHX3; NR3C1; PAX2; NR0B2; TAF7L; E2F4; RSF1; ZNF571; ZFY; ZNF202; ZNF669; SUPT5H; ARID3A; ZNF419; EN1; ARID3B; YEATS2; IFNB1; UBTF; TFEC; KLF3; ZNF580; ZNF91; TONSL; EHMT1; ZNF337; PITX2; CEBPE; ZSCAN32; LHX2; HOXB13; PPRC1; RING1; SKIL; ZNF250; SHOX; ZSCAN9; RELA; ZNF154; IRF6; ZBTB48; ZFP30; ZNF665; GBX1; OVOL2; EGR4; HOXD11; ZNF75D; HOXC8; ZNF8; BARX1; ZIC3; FOXC2; SOX17; ZNF536; ZNF710; EGR2; KLF11; SMARCD2; AFF2; ZNF415; ZNF587; BRWD1; LHX6; RXRG; INSM1; AR; ZBTB43; JUP; ING4; DLX5; PHF20; ZNF219; ESR1; ZNF268; ZFP2; OSR2; MYT1; ALX3; GFI1B; ZNF287; HOXC5; MXI1; PKNOX2; ZNF33B; SKI; SUPT7L; TLE2; ZNF85; KDM4A; BNC2; HMBOX1; MXD3; WIZ; TCF7L2; ZNF557; ZNF768; BCL6; RFX2; ZNF165; TBX10; LZTR1; HOXD9; TOX3; MSC; ZNF273; ZNF141; SOX13; ZNF195; GATA4; ZZZ3; HMGXB4; NRL; MDM2; SUPT6H; MAFB; EPAS1; TBX3; CNOT3; HOXB5; ZNF329; SETDB1; NR4A2; ZNF611; DBP; BCL11A; ZBTB39; RARA; CHD4; MEF2C; MED14; PRDM13; CHD9; YBX2; FOXL2; ATF2; FOXN2; PAX6; NKX2-2; SAP18; FOXJ1; NCOA2; RORA; ZNF770; SOHLH2; THAP7; CCNH; NKX2-1; TRAK1; MED31; SERTAD2; SMARCA1; ZNF135; SMARCC2; TAL1; GATA6; GRHL2; ZFPM2; PIAS4; AIP; FOSB; CBFA2T3; CAMTA1; EVX1; HOXA3; MED17; POU4F1; ZNF423; ZSCAN31; TCEA2; ZFP37; LMO1; MYCN; ZNF226; NFIC; TOX4; RNF138; RAD21; LHX1; TWIST1; RARB; HOXD10; HEY1; PLAG1; ZNF267; FOXG1; ZNF711; HEY2; NR5A2; ZNF239; NR1H2; TULP3; PLAGL2; ZNF180; CAMTA2; MEN1; OLIG2; ZKSCAN1; POU2F2; ZNF552; ZNF43; EYA1; TBX19; MAFF; SUPT4H1; CD3D; ZBED2; ZNF562; BACH2; TBX21; GATA1; FUBP1; ZNF175; RORC; SUPT3H; HOXB2; ARID5B; PCGF1; TSG101; HIPK1; CREB3L2; BPTF; NR1H4; JUN; PGR; HOXB6; HOXA11; ZNF593; CREB5; ZNF430; KLF1; CIZ1; HLF; PAXBP1; RUNX3; HIPK2; TFCP2L1; ELF3; ZNF671; FOS; JAK2; NFE2; KLF4; VPS72; FOXO1; ARID1A; ANKRD1; ZNF232; TGIF1; ZNF394; NRBF2; ASCL1; ZNF211; LMCD1; FOXI1; MEIS1; PAWR; ZNF83; ZNF24; ZNF134; BIRC2; FOXA2; KLF6; CDYL; JUND; TFDP2; ZSCAN18; CITED2; KAT6B; FOSL2; SRCAP; CITED1; SSBP3; ARNT2; NR1H3; IRF8; BHLHE41; KLF10; ZNF544; FOXE1; SNAI2; NFATC4; PBX3; YAP1; TRIB3; ZIC1; IL16; ZNF281; DDIT3; TCF4; INSR; PBX1; ZBTB20; SPDEF; NR0B1; MTF2; ZNF22; NFE2L3; CRYM; IRF1; KDM5B; THAP10; MECOM; SSX1; SMAD7; TP63; CUX1; KLF9; BHLHE40; TOX; TBX2; AHR; PIR; TLE4; E2F2; NFATC3; ZNF586
Down-regulation 123 MYC; ADRB2; GTF2A2; CCNA2; HDAC2; PARP1; HMGB1; TCERG1; PRKDC; FHL2; EZH2; RBM14; HOXA5; PCBD1; NPM1; RBBP4; PURA; BMI1; BRD3; ZBTB38; ECD; ARNTL2; SUB1; XRCC6; PBRM1; FOXD1; PPARG; TP53; HLTF; SREBF1; MED21; BCLAF1; MED6; CBFB; EED; RUVBL2; SMARCC1; RAN; SMARCE1; HES1; HNRNPD; CEBPZ; NCOR2; BAZ1B; MAGED1; RNF14; EDF1; KLF2; BLM; ENO1; TLE1; MNAT1; LOXL2; TCF20; ZNF292; HMGB3; DNAJC1; PTTG1; PMF1; SSRP1; BAZ1A; HMGA1; BASP1; DNAJC2; TBL1XR1; TRIP6; HOXC6; TSC22D2; PA2G4; ORC2; CTNNB1; TAF9B; BRCA1; ETS2; RREB1; PITX1; ABL1; JARID2; STAT5B; GTF3A; ITGB3BP; ALX1; SIX2; ATF1; AFF1; ZNF32; NEDD8; EGR1; HSBP1; TMF1; SMAD5; TRIM16; CENPF; UBE2B; CTR9; BCL11B; TCEA1; FLNA; CCNC; TFDP1; DNMT3B; JUNB; RBBP7; NRIP1; XBP1; SFPQ; MED1; RBPMS; IKBKAP; HOXB7; TOB1; YWHAB; NR2F2; VEZF1; FOSL1; FOXC1; TAF10; NFIB; ELK3; NKX3-1; HOXC10; SAP30; SATB1