Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15939 Nvp-aew541 GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 77 MEF2C; FLI1; PEG3; ZNF512B; TDP2; HOXD1; EN1; ZNF93; IRF2; HDAC9; ERBB4; TRPS1; PBX1; ZNF665; ZNF302; SMAD3; ZNF721; JUND; MYBL1; DLX5; ZEB1; ZNF189; BCL6; ZNF232; ANKRD1; ZFP36L1; NFE2L3; JAK2; NR1H4; PRRX1; BRD2; CHD9; HIPK2; SALL1; CREBL2; DLX2; ZNF423; ZNF32; LIN28A; ZNF160; ZNF131; SOX17; WT1; ST18; LMCD1; FOXL2; HDAC4; HIPK3; DACH1; FOXG1; ZIC1; INSM1; PAX6; INSR; KLF5; TOX3; TULP3; NANOG; IRF8; KLF11; MAF; NKX2-2; VPS72; MYRF; MECOM; SAP30; TRIB3; ZFPM2; TFAP2C; ZHX2; PBX3; ZEB2; TWIST1; BHLHE41; CRYM; MAFB; CREB1
Down-regulation 22 BCL11B; NR3C1; CCDC59; RNF10; HTATIP2; ADNP2; FOXD1; SPEN; MITF; PURA; EYA2; RBBP7; RNF6; PDLIM1; LEF1; ELF5; IRF4; HMGN3; AFF1; TBX2; KDM5D; E2F2