Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15936 Nvp-aew541 GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 49 MEF2C; GLI2; TSC22D3; TRIM22; POU5F1B; EPAS1; KDM5D; SMAD3; CEBPD; SND1; ZFY; HSF1; E2F3; MYBL1; ZNF22; PBX1; FEZF2; HDAC9; NKX2-1; PTRF; PGR; FOXE1; ZBTB16; HBP1; SMAD6; STAT6; KLF9; BASP1; CUX2; ZNF217; ZBTB38; FOXN3; CARHSP1; TWIST1; PDLIM1; BTG1; TGFB1; HTATIP2; FOSB; CREB3L2; ERG; TRIP6; EGR1; KLF5; SOX17; TCF4; MYT1L; ID3; CRYM
Down-regulation 42 CNOT6; MYCL; MXD1; CHD7; LEF1; CREG1; HSF2; SMAD1; CERS6; SATB2; ZBTB11; RNF138; ZNF45; STAT1; URI1; MLXIP; SP140L; TBPL1; MYB; MNDA; KAT2B; TBL1X; TOB1; TCEA2; SCAND1; AEBP1; TCF7L2; EYA1; ASCL1; ZBTB18; CREB1; TP63; PITX1; DACH1; HOXC10; RUNX3; MAFB; HMGN3; ZHX2; MAF; GATA2; ZNF586