Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15934 Nvp-aew541 GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 94 TSC22D3; SREBF2; NCOA3; ZNF652; HOXA10; ZNF611; ZNF224; ZNF160; CARF; SOX4; TFEC; BTG1; ZNF264; KLF6; ZNF665; ZNF430; YEATS2; CALCOCO1; ZNF426; INSM1; ELF3; TOX3; ETS2; IRF7; PNRC1; EPAS1; CREBL2; POU5F1B; AHR; HOXD1; NFIL3; PEX14; L3MBTL1; IRF5; ELF4; TSHZ2; ZKSCAN1; FOXO3; ZNF536; HIVEP2; HDAC5; KLF5; FOXD1; HBP1; PHF20; REL; ERBB2; SMAD3; LITAF; SMARCA1; ZNF512B; ZNF721; GLI2; SREBF1; STAT6; POU4F2; PAWR; CUX2; CREB3L2; HDAC9; NFAT5; MITF; HIPK2; BHLHE40; ERG; PBXIP1; ZNF331; MEIS1; ZNF83; FOXF1; FOSB; HIRA; CARHSP1; NR1H3; ELF5; FOS; MYRF; PPARGC1A; PDLIM1; PLAGL1; PBX1; TRIB3; MEIS2; JUP; CREG1; ARNT2; CRYM; TRPS1; ZNF91; BASP1; FOXO4; SOX9; GATA6; KDM5D
Down-regulation 66 CCNA2; MYCBP; EED; GTF2A2; GMNN; MYBL2; RUVBL1; EZH2; TFAM; WDR77; ADRB2; TOPORS; CCDC59; CARM1; ZNF473; HSF2; ZEB1; RRN3; BAZ1B; PPRC1; ECD; SNIP1; C1QBP; TAF5; PRKDC; UBP1; PA2G4; LEF1; CEBPG; ZNF200; DNAJC2; URI1; PTTG1; NPM1; SUB1; TRRAP; RBBP8; SMAD1; RBM14; PBX2; SF1; CEBPZ; HMGB1; SUV39H1; TBPL1; ITGB3BP; RUVBL2; TRIM28; BRCA1; WT1; FOXA2; CCNC; CCNE1; SMAD7; AEBP1; EGR3; IKBKAP; NR2F1; MECOM; ZSCAN18; FOSL1; SATB1; GATA2; BHLHE41; ETV1; IKZF1