Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15932 Pf-431396 GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 50 BTG1; NR1H2; ATF3; ELF3; VGLL4; BANP; PNRC1; HOXD3; BNC2; HOXD1; MYCL; HMGB3; ZFP36L2; RARA; OSR2; IRF7; IRF9; MEIS2; TGIF2; TCF7L1; FOSL2; ESR1; IFI16; REL; PBX1; SOX17; EMX2; DACH1; PBX3; TP63; EYA1; MXI1; KLF6; CREB3L2; CTBP2; DDIT3; SIX2; WT1; TRIB3; ZNF331; KLF4; ZNF165; RFX5; GATA6; KLF2; TFAP2C; INSR; ZHX2; SOX11; CREB1
Down-regulation 42 FOSL1; SMARCA4; CENPB; HMGA2; MLXIP; DEK; DRAP1; PMF1; TEAD1; MYB; CRY1; NRIP1; NPM1; PRKDC; CD3D; RNF141; HMGA1; ATF5; SPEN; TXNIP; NFAT5; EGR1; CEBPA; ENO1; CTR9; ST18; SFPQ; MYT1L; RBPMS; TRIM28; SATB2; BMI1; SOX9; ZBTB38; RUNX3; SMARCA2; ELK3; NFIB; SATB1; KDM5D; ETV1; GATA2