Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15930 Pf-431396 GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 82 TSC22D3; TEAD3; TRIM22; ZNF467; WNT4; NR1H2; DLX2; HSF1; EMX2; BNC2; OSR2; HDAC9; PNRC1; HBP1; SALL2; TAF6L; RFXANK; SOHLH2; IFI16; INSR; VDR; IRF8; CREBL2; GATA6; SRCAP; TEAD4; PBX3; ZNF331; RUNX1; ZNF44; IRF9; TULP3; MXI1; ELF4; ZNF512B; PBX1; GLI2; BCL11A; MYCL; PBXIP1; WWC1; TRIM29; LITAF; ZMIZ1; SOX2; BTG1; CTBP2; THAP11; SP110; REPIN1; TCF7L2; TCEA2; IRF6; TRIB3; TFAP2C; WT1; VGLL4; MEIS1; ZFP36L2; KAT2B; MEIS2; ZNF43; FOSB; CREB3L2; NFE2L3; CUX1; KLF11; ARNT2; ZHX2; ATF3; JUP; ZNF165; TP63; ID4; NFIB; AEBP1; MNDA; ZNF91; MAF; ARID5B; NR2F6; ID1
Down-regulation 56 CCNA2; HMG20B; RBM14; TFAM; ZBTB38; TOPORS; HMGB1; DRAP1; COPS2; NR1D2; CCDC59; HSBP1; BMI1; CTR9; TEAD1; RNF141; PMF1; EGR1; NUP62; XBP1; SUV39H1; FOXG1; TCF12; TBPL1; CENPF; SPEN; ETS2; SATB2; ITGB3BP; BATF; BLM; FOSL1; NFAT5; CTNNB1; SALL1; MED1; TAF10; SUB1; CHD7; ENO1; BHLHE40; PIR; EGR3; HLF; ZFP36L1; MYT1L; IRX5; LEF1; TOB1; MSX1; PITX1; ELK3; SATB1; ETV1; EGR2; KDM5D