Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15926 Gsk-1059615 GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 77 NCOA3; ZBTB16; ZBTB3; CALCOCO1; CBFA2T2; PNRC1; CBX7; TSC22D3; TGFB1I1; LIN28A; HOXD1; ZNF623; ZNF74; BNC2; HDAC5; ZNF573; CREBL2; ZNF611; TEAD3; TLE2; SOX3; SALL2; PEX14; GLI2; ZNF112; ZNF12; MED14; MYBL1; BARX1; NANOG; TCF21; TERF1; NCOA2; FOXF2; E2F3; NR1H2; ZNF350; FOXN3; FOXO1; TRIM22; HIC2; PBX1; STAT6; WNT4; TULP3; PKNOX2; LOXL2; RERE; SOX17; TCEA2; ZNF423; OSR2; NR5A2; SMAD6; ZNF512B; ZNF331; ZBTB20; ARNT2; ZNF117; FOXF1; ZSCAN18; ZEB1; PBX3; MYCL; HIPK1; CTBP2; KLF11; AR; TWIST1; MEIS2; JUP; ID4; CRYM; TCF4; TOX; SNAI2; NFATC4
Down-regulation 38 ETS1; CCDC59; DRAP1; ATF5; GATAD2A; TFAM; AFF4; CTR9; JUNB; RBM14; ARNTL; MED1; MTDH; BMI1; UBP1; EGR1; MED24; SERTAD2; XBP1; PITX1; SUB1; IRX5; SOX9; TRIM16; CHD7; BHLHE40; TOB1; TRIB3; HOXC6; FOSL1; MSX1; KLF2; SATB1; HOXC10; TRIP6; AFF1; ETV1; KDM5D