Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15925	Gsk-1059615	GSE70138	MCF10A	Human	24h	1.11uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	120	NFKBIB; TSC22D3; HOXD1; PNRC1; CALCOCO1; NCOA3; IRF9; KAT2B; HDAC5; HOXD3; SOX4; PBXIP1; MED12; HDAC6; BTG1; MECP2; CEBPD; ZNF33B; STAT3; ATF2; SSBP2; CBFA2T2; ZBED1; PHF20; ZNF467; YEATS2; EZH1; CIR1; SIX2; ZNF112; MEOX1; PRPF6; BPTF; ZNF623; FOXO3; ZBTB16; NR1H4; CREBL2; PCGF3; RBFOX2; BCL6; BAZ2B; SMARCC2; MNT; ZNF239; EYA1; MED14; ZNF350; SMAD6; VGLL1; MXI1; FOXN3; ARID4B; PHF1; BRD4; TCF25; ELF4; CHD9; ING4; ZNF217; ZNF544; ERBB2; WT1; HDAC4; LPIN2; SALL2; SMARCA1; TCEA2; IFI16; PHIP; SP110; TCF21; ID4; TXNIP; LIN28A; BRD8; TRIM22; HBP1; MYCL; FOXO1; TSC22D1; TCF7L2; ZNF232; REL; KLF6; ZNF268; THAP4; TULP3; CUX2; REPIN1; ZNF91; ARNT2; NR5A2; TOX; LMCD1; NFE2; THAP11; SOX2; BCL11A; ZNF423; TCF7L1; SOX13; PBX3; RFX5; CREB3L2; ERG; BACH2; TRIB3; HMGN3; MECOM; LITAF; MEIS1; SNAI2; ZHX2; CRYM; MEIS2; TLE4; ZSCAN18; ARID5B; KDM5D
Down-regulation	84	CCNA2; GTF2A2; MYBL2; HMGB1; DRAP1; MYCBP; HDAC2; PRKDC; RUVBL1; RAN; NUP62; EED; ATF5; WDR77; BATF3; CHD7; HDAC1; EZH2; SMAD5; SATB2; RBBP4; CAPN15; XRCC6; SFPQ; ARNTL; TFAM; GATAD2A; BMI1; ASH2L; XBP1; COPS5; PIAS2; RBM14; FOSL1; MED24; RBBP7; FOXF1; HOXA1; HLTF; PRRX1; DNAJC2; SUB1; SUV39H1; BCLAF1; CERS6; EGR1; TRRAP; PA2G4; BHLHE40; MSX1; SREBF1; MITF; JUNB; BLM; CBX6; HOXB7; C1QBP; HSBP1; ZBTB18; CTR9; HNRNPD; TRIM16; CBFB; RUVBL2; PITX1; TRIP6; BIRC2; PTRF; FOXA2; RREB1; TFDP1; SOX9; EGR3; TRIM28; FLNA; MYT1L; IRX5; SMAD7; RUNX3; TBX3; NR2F1; ETV1; ELK3; SATB1