Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15924 Gsk-1059615 GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 197 TSC22D3; HDAC6; PNRC1; SOX4; NCOA3; CALCOCO1; HBP1; BTG1; ERBB4; ZKSCAN4; CEBPD; HOXD1; MXI1; EZH1; CBX7; SALL2; ZNF532; TCF7; CARF; NFE2L1; ZNF688; TRIM22; KAT8; CIR1; MED12; L3MBTL1; SPI1; ZNF33B; DMTF1; ZBTB3; ZNF219; PCGF3; NR3C1; NFIL3; ZBTB16; IRF9; ZNF623; ATF3; ZNF358; ZNF34; CBFA2T2; MZF1; YEATS2; ZSCAN9; CITED2; HINFP; FOXN3; ING4; SMAD4; PBXIP1; TFAP2A; CREBL2; BAZ2B; ZNF12; RSF1; ZNF345; ZNF768; MEIS1; ZSCAN16; ZNF112; APBB1; HDAC5; ZNF222; ZNF467; TRIP4; ZNF133; ZNF225; FOXO3; HDAC9; AIP; NR4A2; SMAD6; SMARCA1; PEX14; ELF4; TCF7L1; SMAD2; ZZZ3; ZNF589; TCF25; ST18; TFEB; PHIP; ZNF711; BRWD1; TCEA2; SOX3; ZNF24; ZNF354A; ZNF7; TLE2; TP63; ZNF536; AEBP1; ZNF175; BPTF; ZNF606; ZFHX3; AHR; ERBB2; ZNF141; TGIF1; INSR; ZNF331; ARID1A; KAT2B; ZNF223; ZNF248; SOX2; SP2; ZNF45; ZNF117; DAXX; ZIC3; JUND; ZBTB17; BCL11A; SETDB1; ZNF444; TFEC; THRA; CUX2; CAMTA1; ARID5B; BRD8; ZMYND8; ZNF423; BRD4; ATF4; JUP; BASP1; FLI1; PHF20; ZKSCAN1; ZNF415; ZNF304; ZNF44; TFDP2; PBX1; DDIT3; HOXB2; INSM1; TULP3; ZNF160; TRIB3; ARNT2; NAB1; NCOA2; NR1H3; MBD2; TAL1; WNT4; ZNF281; SP100; BCL6; AES; PPARGC1A; TRIM29; KLF11; ARID4B; ZNF43; MYRF; KLF5; SSBP3; ZFP36L2; PAWR; KLF13; SAP30; ID3; FOS; PAX5; FOXA1; ZNF217; FOXO1; MNDA; WT1; IRF6; MEOX2; ZFPM2; TOX; FOXO4; BACH1; SSBP2; ZNF165; MEIS2; VGLL4; KLF9; TRPS1; TSC22D1; ZNF91; GATA6; PCGF2; HEY1; NFATC4; TCF4; HMG20B; CREB1
Down-regulation 109 TCERG1; CCNA2; GTF2A2; MYCBP; PARP1; PPRC1; ADRB2; RUVBL1; DRAP1; HDAC2; ATF5; GABPB1; EED; SUB1; NPM1; RAN; WDR77; NOC2L; C1QBP; MYBL2; PA2G4; MLX; EZH2; CRY1; BAZ1A; FOSL1; RBM14; TFAM; LZTS1; CHAF1B; ABT1; MYBBP1A; DDX54; NFKBIB; CBFB; PCBD1; TBP; BATF3; HMGA2; GATAD2A; MLXIP; MYF6; ILF2; EGR1; ELK1; DNAJC2; EDF1; TAF9; HES1; CTR9; ZBTB24; HMGB1; PSMC3IP; RBBP4; BMI1; EGR4; CEBPZ; CCDC59; SUV39H1; NUP62; CHD7; TRRAP; DNMT3B; BHLHE40; SFPQ; RUVBL2; ZFHX4; RNF6; BCLAF1; TFDP1; ALX1; TEAD1; TSC22D2; ENO1; KLF2; NFIB; SATB2; TRIM25; TEAD4; CCNE1; PITX1; ZBTB18; HNRNPD; WWTR1; MYB; MTDH; HSBP1; SF1; CREB3L1; EGR3; HOXC10; HLTF; YWHAB; CCNC; HOXC6; NR2F2; KAT6B; IRX5; MSX1; TRIM28; PLAGL1; IRF4; KLF4; PUF60; ELK3; ZBTB38; SATB1; ETV1; IKZF1