Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15920 Barasertib-hqpa GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 33 TBX2; PHF20; SMAD5; FOXD1; SERTAD2; MTDH; PTTG1; HLTF; ESRRG; VDR; RFX5; TCF7; TRIM22; MBD2; FLNA; ZBTB38; ELF1; TBL1X; SFPQ; LEF1; FOSL2; JARID2; HOXB7; DACH1; MYT1L; TGFB1; TOX; BASP1; KDM5D; ZBED2; ELK3; SATB1; HOXC6
Down-regulation 55 ATF5; RBPJ; CTBP2; SMAD1; USP22; TCF7L2; LIN28A; ERG; YBX3; SMARCC2; KLF4; CHD9; CRY1; PAXBP1; ZBTB16; ETS2; FOXO1; CUX2; CITED2; TAL1; NFE2L3; PLAGL1; NR5A2; CCNE1; TFAP2C; ZBTB18; TULP3; LMCD1; ELF5; LITAF; NANOG; RYBP; PBX3; ZEB1; E2F8; ZNF423; HHEX; AR; MYCL; KLF11; SOX11; GATA6; CBFA2T3; TCF4; MNDA; ZIC1; OSR2; CREB1; MAF; ZNF91; NFATC4; E2F2; GATA2; ZNF586; IKZF1