Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15916 Vemurafenib GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 41 KDM5A; MNAT1; SIX1; RSF1; PBX1; PLAGL2; MEF2A; NFAT5; RARA; HEY2; NKX3-1; MYBL1; SERTAD2; ASXL1; BBX; SPDEF; ZNF22; MKL2; TCF3; CNOT3; SMARCA1; FOXG1; TGIF1; CALR; MEIS1; ERBB4; SOX9; ZBTB18; RXRA; FLNA; OSR2; NKX2-2; GATA2; VPS72; MAGED1; ZBTB38; TBX3; NFIB; CRYM; HOXB2; BHLHE41
Down-regulation 27 PAX8; LEF1; HDAC1; AEBP1; HMG20B; CREG1; MLXIP; MYCN; SHOX2; FOXD1; VDR; ETS2; TCEB2; CTBP2; ASCL1; BIRC2; FOSL2; PIR; KLF4; HOXC6; TOB1; TSC22D2; MAFB; MAF; TLE4; SATB1; E2F2