Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15915 Vemurafenib GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 38 ZNF589; CTBP1; NKX2-1; PRKDC; IKZF1; ZMIZ1; TFEB; DEAF1; FOXJ3; POU2AF1; NFE2; CEBPA; LEF1; ZBED2; TCEA1; IRF9; TCF3; NCOA2; EGR1; PDLIM1; DDIT3; IRF1; VPS72; ZNF232; ZFP36L1; ZBTB18; PAX5; TCF7L2; TCF4; ZNF652; ID3; INSR; IRF4; TLE4; ZSCAN18; BHLHE41; PBX3; ID1
Down-regulation 32 TOX3; TEAD1; RBPMS; MED1; INSM1; MYCN; PEG3; NR1H4; EPAS1; ST18; BTG1; BRD2; NR4A3; STAT3; MEIS1; PBX1; OSR2; FOXF1; NKX2-2; NR4A2; BRIP1; CITED2; EHF; NR2F1; ASCL1; BASP1; ZFPM2; TRPS1; FOS; EMX2; GATA2; CREB1