Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15913	Vemurafenib	GSE70138	MCF10A	Human	24h	1.11uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	69	LYL1; TFEC; SMAD6; SP140; FLI1; PPARGC1A; E2F3; NEUROD1; TRIM24; NCOA1; TOX; SOHLH2; CDX2; ZEB2; SUPT3H; SMARCE1; HIPK3; ZNF175; FOXF1; ANKRD1; DACH1; ZNF217; SOX10; RARA; FOSL2; MSC; ZNF22; ZFPM2; SOX17; CTNNB1; KLF1; XBP1; CHD7; NR3C2; PTTG1; HEY2; NPAS2; HMGB3; IRF1; HLTF; CREM; WT1; ERBB4; FOXA2; ID2; TCEA1; POU2AF1; STAT3; TAL1; STAT4; NFE2L3; BRCA1; FLNA; LMCD1; NFIB; ZBED2; SMAD7; AHR; BMI1; SSX1; TXNIP; KDM5D; SAP30; CALR; MNDA; ZBTB38; ZBTB18; GATA6; ELK3
Down-regulation	64	TAF5L; TDRD3; COPS2; TFCP2; CCDC59; BRD4; ZNF532; TOX3; SHOX2; SOX15; BAZ1B; MZF1; FOXD1; CALCOCO1; ZNF12; MEIS2; TWIST1; NR4A1; MNT; SUZ12; OSR2; ING3; STAT6; PIAS1; HEY1; ZFHX4; SOX4; ZNF692; ZNF331; ZNF394; IRF9; DLX2; TCF4; RNF6; TAF10; BRD2; ELF5; CTBP2; CITED2; SMARCA1; ARID1A; ZNF281; MED1; ZNF264; PBX1; SIAH2; TOB1; HIRA; KLF4; SPIB; HOXB2; TFAP2C; IRF8; FOXG1; CREB1; MAF; TRPS1; HOXC6; PEG3; TBX3; ZNF423; KAT6B; GATA2; NFATC4