Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15912 Vemurafenib GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 39 RBBP8; TSC22D3; RSF1; PAWR; SETDB1; TBL1X; TOX3; ID4; HLX; OVOL2; PNRC1; SREBF1; ZNF165; XBP1; HIRA; NFE2; YAP1; ZNF131; FOXA1; ARID5B; MYCL; EGR1; WT1; NKX2-1; SALL2; ZNF512B; FOXF2; BAZ1A; TRIB3; TCF4; AEBP1; JUP; ESR1; BCL11A; ARNT2; LMCD1; FOS; ID1; NFATC4
Down-regulation 35 ADRB2; ZNF432; RNF14; MED21; ZNF443; SIM2; BMI1; CRY1; ATF7IP; CTR9; MYCN; NELFB; ARID4B; ZEB1; ARNTL2; MED13; HMGB2; SMAD7; ELK3; ERG; ZIC1; ZBTB38; RXRA; RFX5; NR2F2; HMGN3; MSX1; KAT6B; HOXC6; ZEB2; CREB1; GATA2; BASP1; EGR3; EGR2