Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15911 Vemurafenib GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 54 TSC22D3; MNAT1; ATF4; SLC2A4RG; SIX1; ZNF467; MAFG; CALCOCO1; MED12; CREB3L1; TRIB3; DDIT3; ATF3; SMARCD3; MED14; IKZF1; TCEA1; NR1H2; ZMYND8; TGFB1I1; PBX1; XBP1; HBP1; TGIF1; E2F5; TRIM29; TBL1X; TCEA2; TWIST1; IRF9; NR1H3; KLF5; KLF13; LOXL2; HIRA; FOXF2; SIX2; ZNF217; MYRF; VPS72; AHR; LMCD1; MECOM; ID4; ID1; HEY1; ARNT2; TRPS1; SNAI2; BASP1; HOXB2; SOX9; EGR2; NFATC4
Down-regulation 44 ADRB2; SMARCA4; ZNF468; EED; CRY1; SOX4; RRN3; RNF14; NRIP1; ZNF443; MYB; ING3; ZNF266; ECD; NPAT; CDK8; TBPL1; NUP62; BRD2; BCLAF1; MAX; CEBPZ; TSC22D2; BAZ1A; SFPQ; CTR9; BMI1; SUB1; RBPMS; KLF10; BIRC2; RFX5; HOXB7; DNMT3B; HOXC6; MSX1; ZBTB18; AFF1; RELB; ASCL1; NR2F2; SATB1; CREB1; ETV1