Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15905 Nu-7441 GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 127 KDM5A; SUV39H1; NCOA3; MECP2; TSC22D3; PQBP1; NFKBIA; ELF4; BTG1; INSM1; TFAP2A; TAF1; CALCOCO1; HDAC5; CEBPD; SPI1; NEUROD1; BARX1; PHF20; SRCAP; HBP1; DYRK1B; NFATC3; TSG101; CRTC1; HOXD1; BAZ2A; ZNF611; PRDM12; NFE2L1; ZNF224; SUPT6H; MED14; BBX; TFE3; ZNF467; ZKSCAN1; HOXA5; ZNF160; MXD4; PFDN5; CHD4; MXI1; SIN3B; HOXB1; ZBED1; RORC; KLF13; BPTF; MNT; EHMT2; PNRC1; MZF1; JUP; CBX4; TGIF2; SOX3; SOX4; NFE2; SMAD6; ZMYND8; ZNF665; NFAT5; FOXN3; ZBTB16; PBXIP1; ZMIZ1; BCL6; TCF7; ZNF589; ATF3; ZNF350; ZNF573; TXNIP; TOX3; HOXB5; FOXF2; ZNF652; ERBB4; E2F5; BCL3; RARG; WNT4; KDM5D; PBX1; SNAI2; BCL11A; DLX5; CDYL; PAWR; SALL2; REL; ID2; IRF9; ARNT2; LOXL2; PLAGL1; STAT3; HHEX; ZNF165; CREB3L2; ZNF91; FLNA; ZSCAN18; FOXF1; TCEA2; PEG3; HEY1; KLF5; OSR2; MYCL; VPS72; SCAND1; AR; FOXG1; CUX1; TRIB3; SSBP2; NFATC4; PAX5; TCF4; RXRA; TGFB1; TRIM29; TRPS1; CREB1; ID1
Down-regulation 86 CCNA2; ADRB2; EZH2; TCERG1; SUB1; MYBL2; FOXM1; GABPB1; EED; RBM14; TBP; HSF2; CCDC59; BAZ1B; HMGA2; HMGB2; HMGB1; WHSC1; NFKBIB; CENPF; CRY1; PTTG1; LEF1; CHAF1B; ZNF532; PRKDC; RBBP4; NUP62; SAFB2; BCLAF1; DR1; FOXD1; ZNF107; DEK; HOXB7; PAX8; WDHD1; PSMC3IP; BMI1; RRN3; HMGA1; ECD; TAF9B; ZNF266; HOXC6; TRIM32; HLTF; HOXA1; BRCA1; CTR9; ELK3; MED6; BATF3; TBPL1; PHOX2B; FOSL1; XBP1; TRIM28; PSIP1; DNAJC1; CBX3; TBL1XR1; HNRNPD; SMARCA2; CCNC; SAP30; BCL11B; RUVBL2; BLM; NFIB; DNMT3B; TFDP1; CBFB; AFF1; KLF2; IRF4; TSC22D2; HOXC10; SOX11; NR2F2; VGLL4; MAFB; CDK2; PITX1; GATA2; BHLHE41