Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15902 Pd-0325901 GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 394 TSC22D3; SUV39H1; CALCOCO1; PNRC1; ZKSCAN4; IRF9; CSDC2; NCOA3; ZSCAN31; HOXC13; DLX4; ZNF611; EZH1; ZNF688; AFF2; HBP1; MXI1; ZIC3; PBXIP1; ELF3; ZNF701; CDIP1; ZNF257; TULP2; HINFP; ZNF500; ATF3; CBX4; LMO1; NFE2L2; ZNF669; ELF4; FOXF2; NR5A1; DYRK1B; ETV3; THRB; ID4; TFAP2A; PRDM1; RSF1; RFX1; HIF3A; ZNF223; CHD2; DCC; PRDM14; ZKSCAN3; AES; IRF6; ZNF44; CARF; ZNF221; ZBED1; ZNF768; MEIS1; ZNF112; MAML3; SRY; ZSCAN9; HESX1; ZIC4; EMX1; BRCA1; SCAI; HOXB5; ADRB2; ZNF76; ZNF345; NR6A1; ASCL3; NEUROG3; EPAS1; ZKSCAN8; ZNF770; ZXDB; CREBL2; RFX3; PROP1; NKX2-5; ZNF467; KLF3; ZNF589; FOXH1; KLF15; SALL2; HOXB2; DLX5; TBX5; SREBF2; KDM5C; JUNB; ZNF573; ZKSCAN1; POU2F3; ZNF33B; RARG; OSR2; OVOL1; ERBB4; TULP1; PAWR; ZNF510; DLX2; ZNF665; TUB; ZBTB44; ZNF117; TBX4; SP1; ZNF225; ZNF682; TRIM16; HES2; HOXB8; SPI1; SP4; VENTX; ZBTB3; BAZ2B; ZNF480; SSX7; HOXB1; ZNF254; HMBOX1; NRL; JUND; ZNF141; TP73; ATOH1; JUP; HNF4G; RARB; LHX3; TEF; ZNF93; NR1H2; WNT4; MED12; RING1; CASZ1; ZNF675; ZNF81; HDAC11; ZNF506; ZNF174; SOX21; ZNF85; TFE3; ZNF536; TAF1C; SHOX; ZMYND8; PIR; SOHLH2; SIX3; NCOA2; ZNF160; NEUROD4; NR0B2; PAX1; ZNF136; BNC2; MED25; MKL1; PRDM12; ESRRB; ZNF154; NFIC; ZNF407; TFDP3; HOXC11; PIAS4; ZFHX3; NEUROG1; NFE2; SOX3; DDX17; TFEB; MYF5; BCL6; NHLH1; MED16; BARX1; GBX1; FOXF1; CBL; INSM1; PIAS1; EYA3; TBX10; BTG1; ZNF224; CEBPD; POU6F2; ARID3B; ZNF721; WHSC1L1; SSBP3; CBX2; PLAG1; HDAC5; TAF6L; TLX3; RORC; HOXD1; ZNF710; NFIX; SUPT7L; MZF1; SMAD6; ZNF711; ZNF264; TAF7L; L3MBTL1; GFI1B; CERS4; ZNF165; PHF20; ZNF816; ZSCAN16; E2F5; BCL11A; MED14; KLF5; ZNF623; KDM4C; ZNF133; ING4; ZNF571; VGLL1; TBX1; FOSL2; ZNF132; ZNF771; ONECUT2; ERF; BRWD1; FEZF2; ZNF75D; MEF2C; ZNF235; MEIS2; TRIM22; ZNF253; REL; MBD4; MED31; ZMIZ1; PEX14; FOXO3; GATA1; NR1H3; SOX13; RORA; GLI2; SRCAP; FOXA2; ZXDC; HOXB13; CBX7; SOX4; ATN1; PAX6; ZNF415; ZNF667; CIITA; ZNF350; ZNF74; GATA6; FOXO1; SP2; ZNF426; EYA1; KAT2B; TOX3; IRF1; TRIM29; RFXANK; CIR1; VPS72; BPTF; ZKSCAN7; RARA; SOX18; STAT2; FHL5; EP300; NFKB2; TCEA2; PBX1; ZNF652; KLF13; MECOM; HAND1; HEY1; MXD4; ZBTB20; TP63; CREM; ZNF606; NR4A3; PPP1R13L; CAMTA1; EHMT2; TP53; MEN1; HOXB6; PHIP; HDAC9; ZNF444; TCF7L1; ZNF512B; ZNF43; SOX17; ZBTB17; NKX2-1; HOXD11; SOX2; DBP; NR4A2; ZBTB16; PROX1; GRHL2; NR5A2; NFATC1; SMAD3; MEOX2; KLF1; AR; KLF9; TGIF2; ERBB2; LITAF; TLE2; TFEC; CUX1; THAP10; GTF2I; MYCN; SMARCA1; HLX; NEUROD1; CITED2; NLK; CUX2; KLF7; TFDP2; TRIB3; TCF21; CBFA2T3; ZNF91; HLF; TBX3; MYBL1; CRYM; MYRF; MYCL; FOXE1; E2F8; FOXA1; FOSB; HIC2; ZEB1; RFX5; ARID5B; ID2; SPDEF; ZSCAN18; NFATC4; SIAH2; ZNF331; DACH1; TBX2; JUN; ZIC1; STAT4; ID3; ISL1; EHF; LMCD1; AHR; KLF4; TRPS1; CITED1; TOX; TCF4; SSBP2; TWIST1; ARNT2; PBX3; ESR1; ID1; SNAI2
Down-regulation 118 CCNA2; HMGA2; PDLIM1; ABL1; TCERG1; FHL2; NPM1; EZH2; CENPF; PPRC1; PARP1; FOXM1; BAZ1B; FOSL1; HMGB2; PTTG1; TBP; EGR1; MYBL2; ING3; MYCBP; CCDC59; NFKBIB; HLTF; HMGB1; DEK; NUP62; WHSC1; DNAJC2; PA2G4; EED; TFAM; HDAC2; CRY1; CBFB; MYC; PURA; BMI1; RNF4; SMARCA5; HNRNPD; TRIM28; RNF138; RAN; BATF3; EDF1; SATB2; DRAP1; HMGA1; CHD7; SFPQ; BRPF1; SSRP1; TFDP1; ZMIZ2; RBM14; TTF1; CHAF1B; NFIB; SMARCE1; RBBP8; SNW1; DR1; ITGB3BP; MED1; BCLAF1; TBPL1; DNAJC1; PBRM1; UBE2I; ZNF267; XBP1; RUVBL2; SND1; FOXJ3; NRIP1; NFKB1; ETV5; YWHAB; ILF2; SF1; WWTR1; CBX3; ENO1; MLXIP; BAZ1A; CCNC; FOXD1; MAGED1; C1QBP; CTR9; ZNF22; SMARCA2; ELK3; NCOA6; VEZF1; CEBPG; ENY2; CEBPZ; SERTAD2; USP22; ATF1; KLF2; ING2; HOXC6; HOXB7; BIRC2; ELF5; EGR3; SMAD1; AFF1; NR2F2; ETV1; TRIP6; NKX3-1; SAP30; MSX1; CREB1