Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15897 Hg-5-113-01 GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 94 GATA3; ZNF589; FOXO4; LYL1; ATN1; SUPT6H; MED12; ARID3A; MLXIPL; FOXJ1; ARID3B; SIRT2; PHOX2A; HOXC8; TFAP2A; KDM5C; NFE2; EPAS1; EZH1; TGFB1; HIC2; PLAGL1; DLX4; KLF1; CTR9; TRIM22; NONO; ZNF33B; CNOT2; SMAD6; DYRK1B; HMX1; HOXC4; PRDM14; ERF; SLC2A4RG; FOXL2; CIC; GATA1; NAB2; LDB1; MECOM; TDP2; IRF7; STAT6; BARX1; NR4A1; LIN28A; REL; TRPS1; IRF8; ATF3; NR1H4; SIX3; CALR; SP100; IRF9; SMAD3; NR2F1; KLF3; TCEA1; SOX13; VPS72; RBBP7; CREB3L1; NCOA2; TCF21; ID4; HHEX; FOXF2; ERBB4; XBP1; KLF13; JUN; RBPMS; ZNF331; ID1; GATA2; POU2AF1; ZNF512B; MXI1; CRYM; NANOG; CBFA2T3; TRIB3; HOXB2; ARNT2; SOX9; FOXC1; HEY1; SSBP2; ESR1; TOX; NFATC4
Down-regulation 52 TOX3; PTTG1; TLE1; CRY1; NAB1; CERS6; SMARCA4; EDF1; PHF2; TFAM; ETV5; BATF3; TRIM32; ARID4B; RBL2; ZNF32; BRD7; CDK8; BCL11B; SMARCE1; TXNIP; ARL2BP; NKX3-1; MLXIP; ZNF302; MED1; PURA; TGFB1I1; SATB2; BRD8; AEBP1; KAT7; PMS1; NEDD8; MAGED1; SP3; MYB; YWHAB; KLF11; BAZ1A; ZNF281; KLF2; BMI1; ZBTB18; ELK3; FOS; MAFB; PCGF2; CITED1; ZEB2; MSX1; KDM5D