Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15435	Mitoxantrone	GSE70138	HUVEC	Human	24h	10uM	EID0118

Response Information :

Types	Number	Response transcription factors
Up-regulation	197	VDR; NFKB2; RUVBL1; TFAP2A; ZXDC; STAT4; CEBPD; PEX2; TP73; GLI2; SOX5; MYBL1; HSF4; NR0B2; USP16; ZSCAN9; NEUROG1; CREG1; HOXD11; SHOX2; GMNN; SOX3; PA2G4; POLR3C; TERF1; ARNT2; E2F4; SOHLH2; SCRT1; MED14; MYCBP; NKX3-2; SREBF2; ZBTB7B; CNBP; TCEA1; CDK2; SALL2; RXRG; RING1; KDM4C; FOXF2; NANOG; PFDN5; NR1H2; TAF6L; RFX1; PRRX2; WDR77; PRDM1; SOX21; PRDM14; ZNF432; BTF3; SUPT6H; ZFP69B; NOC2L; ILF2; ZNF671; DLX2; HOXC4; VENTX; SIX3; PRMT2; TWIST1; NR2F6; NRL; NFIX; BARX1; ZNF423; TGS1; TAF1A; MAPK8IP1; ACTL6A; CNOT3; DLX5; ZNF136; TCF21; OLIG2; SMARCB1; ZNF154; ZNF304; OVOL2; ZNF180; FOXG1; PBX2; BRF2; HIVEP1; MYCL; ZNF415; ID2; C1QBP; TBX5; NFIC; ZNF219; RUVBL2; PAX6; ERCC2; FOXD1; THRB; FEZF2; HIPK2; BRCA1; ZNF682; ZNF835; ZNF654; LIN28A; ZNF93; FOXA2; SNAI2; SUPT3H; SALL1; CALR; ATOH1; NFATC4; BHLHE41; INSM1; ZNF593; ZNF467; ZHX2; PQBP1; ZNF239; PAXBP1; PCGF1; NEUROD1; HMGA1; POU5F1B; HOXC8; MEIS2; RARG; HOXD3; ZFHX4; ATF3; HOXB5; KLF5; ST18; RBBP8; SOX11; SOX2; FOXJ1; VGLL1; GATA1; KDM5C; TDP2; SOX13; TRPS1; ATN1; FOXE1; SKIL; NKX2-1; ZNF165; AEBP1; ESR1; ZIC3; ZIC1; BRD4; KAT2B; TFDP2; FUBP1; MEOX2; SAP18; EYA2; CUX2; SPDEF; MECOM; FOXF1; CREBL2; RORA; TRIB3; ZBED2; HLF; ZNF232; GTF3A; ISL1; POU2AF1; PBX3; EN1; SPIB; LITAF; FOSB; SATB2; EGR1; TXNIP; SSX1; TFAP2C; ID3; TOB1; ZNF331; SOX9; SSBP2; MYRF; ID4; PPARG; DAXX; PSIP1; EMX2; PEG3
Down-regulation	167	MYC; SOX4; FHL2; ABL1; ECD; BRD3; GATA2; NFIL3; PURA; ERG; HMGA2; TAL1; VGLL4; TCERG1; RBL2; MAX; BLM; REST; YBX3; USP22; NR2F2; ZBTB1; STAT3; TLE1; HES1; BAZ1B; ZMYND11; FOXC1; HOXA10; KAT7; NFKBIA; HHEX; FLI1; PHF2; SNW1; IKBKAP; RUNX1; ELK3; TCFL5; KDM5D; BAZ1A; REPIN1; NPAT; RERE; UBE2B; CCNA2; ITGB3BP; BMI1; RREB1; DPF2; TSC22D2; CHD9; PLAGL2; NCOR1; FOXO1; NCOA6; RBBP4; ANKRD1; SMAD5; PRDM4; MLXIP; TGIF1; MTF2; ZNF267; BATF; LIMD1; DACH1; PATZ1; SMAD1; VEZF1; PITX2; NCOR2; ZEB2; ZBED4; MED13; RNF141; NCOA1; TCF12; TRIM22; ZNF652; RNF10; TFEC; KAT6A; ZKSCAN1; MED1; TRIM32; UBE2I; ARID4B; SPEN; ATF7IP; ZNF146; ADNP; NFIB; HIPK3; BASP1; ZBTB38; MTA1; ZMYM2; TLE2; PBRM1; KAT8; TCF4; SMAD3; NFATC1; BHLHE40; HTATIP2; JARID2; NCOA4; CTBP2; ZNF24; HDAC4; ZNF532; LMCD1; BCL10; BRD8; MLLT10; CUX1; TP63; CTR9; PPARGC1A; NPAS2; NFE2; ZNF84; XBP1; SFPQ; ZNF587; TP53; ELF5; FLNA; ZNF12; ELF1; HBP1; ZNF302; VPS72; SMAD2; AFF1; SAP30; HOXC6; PHIP; TMF1; KLF10; WWTR1; PLAGL1; KAT6B; BCL3; SP100; NR2F1; MAGED1; HOXB7; ZMYND8; KLF6; TBL1XR1; SOX17; HMGB3; IFI16; CREB3L2; ZNF512B; TSC22D1; SMARCA2; NR1D2; MAFB; PIR; TGFB1I1; ZBTB16; KLF2; LEF1; ADRB2