Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15344	Alectinib	GSE70138	HUVEC	Human	24h	0.12uM	EID0118

Response Information :

Types	Number	Response transcription factors
Up-regulation	81	MEF2C; HDAC6; CREG1; RELB; KLF11; ID2; EGR1; KAT7; JUNB; ZBTB39; PRRX1; NFE2L3; DLX5; FOS; NHLH1; NR5A2; TAF6; MED6; SMAD5; EGR3; MYBL1; SOX10; ZNF467; IKZF5; WNT4; NR1I3; KLF9; ACTL6A; HHEX; FOXO1; TP63; BCL3; SPIB; NR4A2; HES1; RXRA; TEAD4; ID3; MYF6; HBP1; ZNF140; NR1H3; SSBP3; CBX7; ESR1; DMTF1; JUP; PIR; CITED2; TERF2; GATA3; CTBP2; IRF6; MXI1; HOXA1; RBBP7; ERBB4; IRF9; HLF; CREB3L2; EN1; ID4; CEBPB; SPDEF; FOXC1; FOSB; SNAI2; KDM5D; NEUROD1; NR2F2; ID1; NFATC3; HTATIP2; NR1D2; TBX3; KLF2; TWIST1; LEF1; FLNA; TXNIP; PSIP1
Down-regulation	43	SOX11; ZNF189; ZFHX4; TLE4; ELK3; ZNF165; BANP; CNOT1; ZSCAN18; TCF12; RBPJ; TSC22D2; CDK8; ZNF83; MEOX2; RAN; MTDH; TOX; ZNF354A; CRY1; DDX17; DEAF1; JUND; ZNF329; MAGED1; ETS2; BAZ2B; HIRA; HMGA1; ZSCAN31; HMGB3; TCF21; SPEN; ZNF512B; SMAD7; FOXF1; DACH1; PITX1; POU2AF1; HOXB2; PBX3; ARID5B; EMX2