Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15311	Dabrafenib	GSE70138	HUVEC	Human	24h	3.33uM	EID0118

Response Information :

Types	Number	Response transcription factors
Up-regulation	68	PURA; SMAD4; BRWD1; ADRB2; E2F2; MXD4; MYBL1; E2F5; KLF11; TAF9B; CEBPG; BRIP1; ZMYND11; JUNB; PITX2; JUP; NR0B2; MYCL; KLF4; NKX2-1; SIX2; DLX5; TP63; KAT6A; MLLT10; KLF6; FLNA; IRX5; ELF5; KLF5; PRRX1; POU5F1B; IRF7; ETS2; YWHAB; ZNF165; TRPS1; ATF4; GATA6; LMCD1; GATA3; TOX3; TRIM29; ZBTB38; PAX6; ATF3; NR1D2; HLTF; ZEB2; KLF9; MYCN; ZIC3; IRF6; PAWR; NFATC3; BTG1; TCEA1; PLAGL1; HTATIP2; NEUROD1; ASCL1; LITAF; TOB1; INSM1; TXNIP; SMAD1; TSC22D1; PSIP1
Down-regulation	57	TLE1; ZNF432; ZFPM2; MEIS2; TRIM22; TCF3; PEG3; NPAS2; MNDA; ZNF468; BAZ2A; CHD3; APEX1; TGFB1I1; C1D; SAP30; PFDN5; LEF1; HOXB2; RFC1; ZHX2; CDK2; HOXB6; HNRNPD; BASP1; RREB1; SP3; WT1; SALL2; TCF21; ZNF83; SALL1; IFI16; SMARCA1; ZNF189; ZNF593; SOX13; KLF7; SP100; NR2F2; RBFOX2; ZNF226; ELK3; ZNF22; CD3D; TCF12; ZFP36L1; ZNF91; MYRF; HOXB7; SSX1; ZNF423; SOX11; TLE4; NR2F1; EMX2; ARID5B