Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15295 Gsk-1059615 GSE70138 HUVEC Human 24h 0.37uM EID0118
Types Number Response transcription factors
Up-regulation 57 HOXD1; RCOR3; NR1I2; BRWD1; KLF11; NR5A2; JUP; EN2; KLF13; MYB; KLF9; KLF5; KLF1; ONECUT2; CDX1; ELF4; LHX3; PRRX1; SNAI2; IL16; HIPK2; TXNIP; GATA1; PAWR; ACTL6B; FOXD1; TCF7L2; INSR; ERBB4; ZNF117; CREB5; TGFB1I1; NKX2-1; CERS6; MYT1L; FOXG1; IRX5; PAX6; INSM1; MITF; DLX5; ST18; TOB1; NR1D2; LOXL2; EYA2; PAX5; ZNF423; E2F2; ZFP36L2; ESR1; MYRF; IRF6; GATA6; TOX3; ZBTB18; GATA3
Down-regulation 23 CRK; FOXM1; RNF4; CTR9; CCNA2; HMGB2; STAT1; NR0B1; NFIB; HMGN3; RBPJ; SMARCD3; PIR; MSX1; NKX3-1; LITAF; PSIP1; TRIM16; PBX3; BASP1; MAFB; PEG3; ADRB2