Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15271 Mln-8054 GSE70138 HUVEC Human 24h 0.37uM EID0118
Types Number Response transcription factors
Up-regulation 110 BACH2; ZNF528; IRF4; THAP11; BTG1; SOX10; PHF1; ISL1; ZNF444; ZNF665; HIC2; MDM2; PFDN5; TRIM22; ZNF536; PHOX2B; ALX1; TSC22D3; DLX5; KDM5A; VDR; SPIB; RUNX3; AEBP1; SOX2; PAX5; E2F5; NR1H2; SP140; POU2AF1; SP3; AFF2; SPDEF; LIN28A; CXXC1; SREBF1; MEIS2; RXRG; ZFHX4; TP63; ZBTB44; COPS2; TCF7; HAND1; ZNF215; KLF13; HMGN3; ETV1; NCOR2; WNT4; ZNF552; SMARCA1; FOXA2; ZHX2; ZFP36L1; ZNF195; FOXO1; ZNF532; PRRX1; ZNF711; ZIC3; CHD4; PBXIP1; ARID4B; MYBL1; RSF1; KAT2B; RARA; LEF1; ERBB2; BCL11B; SALL2; HOXB7; TRPS1; EYA1; SSX1; SMAD7; NHLH2; ZMYND8; ZNF721; EYA2; EHF; TRIM28; JUND; KDM5D; AES; SMAD2; TOB1; MYT1L; PAX6; ETS1; SMARCD3; SAP30; MAF; ZBTB18; CERS6; PBX1; CEBPB; TSC22D1; TBX3; HOXB6; RBPMS; TGFB1I1; MYB; KLF2; MTA1; DACH1; TRIM29; GATA6; PSIP1
Down-regulation 65 DNMT1; YBX3; VGLL4; MYBL2; NSD1; CCNA2; CNOT1; ETV4; HES1; RUNX1; SIX1; ZNF274; MEF2A; HOXA10; ARNTL2; KLF10; STAT1; FOXC1; DEK; SUZ12; ZNF266; PBRM1; CBX3; SIX2; PBX3; ELK3; ZFX; ETV5; TULP3; ATF5; SATB1; SIM2; SFMBT1; HHEX; TAF11; LOXL2; MEOX2; ERG; KLF11; MAFF; NPAS2; DBP; ZKSCAN1; PTRF; MNDA; CUX1; OSR2; ZEB1; IFI16; LITAF; WWTR1; CALR; KLF5; SPEN; EMX2; TOX; KLF9; MAFB; NR1D2; SMAD1; ID3; AHR; NR2F2; ATF3; NFATC3