Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID14989	Rucaparib	GSE70138	HUVEC	Human	24h	1.11uM	EID0083

Response Information :

Types	Number	Response transcription factors
Up-regulation	51	MDM4; STAT2; HDAC9; REL; SERTAD2; NRBF2; RARA; RBBP5; BCOR; ZNF224; MED14; TFAP2A; DLX2; SOHLH2; ANKRD1; ZNF12; NFE2; NEUROD1; HOXB5; LITAF; PQBP1; BIRC2; EGR2; TDP2; PPARGC1A; DLX5; DDIT3; FOXF2; MYRF; KLF5; KLF13; FOXF1; ZNF652; MNDA; FOXG1; MYBL1; VPS72; IRF9; CARHSP1; PAX6; SALL1; E2F5; HOXC10; HOXB2; BTG1; TRIB3; HEY1; NFATC3; INSM1; KDM5D; SOX9
Down-regulation	38	ELK3; SMAD1; KLF2; NPM1; STAT3; SMARCA2; NFIB; FLI1; PNRC1; MLXIP; IFI16; RBPMS; JUNB; TRAK1; SUB1; TGFB1I1; FOSB; TRIP6; SMARCC1; NFIC; IRF1; HLTF; BASP1; ZNF91; NR1D2; HTATIP2; ZEB2; ID3; ERG; BMI1; ATF3; TCF4; ESR1; AEBP1; INSR; PSIP1; SOX11; NR3C1